Bioengineered Cystinotic Kidney Tubules Recapitulate a Nephropathic Phenotype [PDF]
Cells, 2022 Nephropathic cystinosis is a rare and severe disease caused by disruptions in the CTNS gene. Cystinosis is characterized by lysosomal cystine accumulation, vesicle trafficking impairment, oxidative stress, and apoptosis. Additionally, cystinotic patients
Elena Sendino Garví +2 more
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Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery [PDF]
EBioMedicine, 2018 The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development.
Valentina Benedetti +9 more
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Exploring mitophagy levels in Drosophila Malpighian tubules unveils the pivotal role of mitophagy in kidney function and diabetic kidney disease [PDF]
Experimental and Molecular MedicineMitophagy has been implicated in kidney function and related diseases. However, a direct analysis of mitophagy in kidney models, including disease models, remains notably lacking.
Kang-Min Lee +8 more
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Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation [PDF]
Scientific ReportsAcute kidney injury (AKI) can progress to chronic kidney disease (CKD), via a mechanism that is still largely unknown. We previously reported that glucosylceramide (GlcCer) acts as a damage-associated molecular pattern (DAMP) during AKI.
Akinori Osada +14 more
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Fine Structure of the Trunk Kidney and Distribution of Its Secreted Exosomes in the Adult Zebrafish
Shiyan dongwu yu bijiao yixue, 2023 Objective To observe the fine structure of the trunk kidney in zebrafish, and to identify its secreted exosomes.Methods The microstructure and ultrastructure of the trunk kidney in zebrafish were observed by light microscopy and electron microscopy, and ...
LIN Jinxing +5 more
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Histological Characteristics of the Kidney in Mongolian Gerbils of Different Ages
Shiyan dongwu yu bijiao yixue, 2023 ObjectiveTo explore the histological characteristics of the kidney in Mongolian gerbils of different ages.MethodsTen Mongolian gerbils of 2, 6, and 12 months old (half male and half female) were selected.
LU Lingqun +4 more
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Expression of Bcl-2 and Bax in mouse renal tubules during kidney development. [PDF]
PLoS ONE, 2012 Bcl-2 and Bax play an important role in apoptosis regulation, as well as in cell adhesion and migration during kidney morphogenesis, which is structurally and functionally related to mitochondria.
Xiao-Feng Song +4 more
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Morphological description and histological structure of the Hedgehog Kidney (Hemiechinus auritus)
Tikrit Journal of Pure Science, 2023 This study was aimed to recognize the morphological description and histological structure of the kidney in hedgehog (Hemiechinus auritus). The morphological results showed that the kidney has a small bean shape and reddish brown color.
Thekra Atta +4 more
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Biology Open, 2021 Histological studies and magnetic resonance imaging were employed to analyze the kidney structure and function of the freshwater mussel, Nodularia douglasiae. The Nodularia kidney consists of proximal, intermediate and distal tubules.
Eriko Seo +2 more
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The relationship between the lesions of kidneys and the different production stages in layers [PDF]
Iraqi Journal of Veterinary Sciences, 2009 In this study seventy case of dead layers from daily mortalities of farm were inspected and in different production stages. 33 cases suffered from renal pathological lesions distributed as 3 cases in preproduction stages, 24 cases in peak of production ...
A. H. Al-Hamadani, M. H. Mohammed
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