Results 141 to 150 of about 18,915 (265)

The miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell injury in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Suppression of miR‐145‐5p alleviates DN‐associated renal tissue damage by inhibiting NRF2/SLC7A11‐mediated ferroptosis of RTECs. ABSTRACT Purpose This study aimed to investigate the molecular mechanism by which the miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN ...
Ganlin Wu, Yu Fang, Meirong Xu, Zuopeng Lu, Yu Cao, Yana Gao   +5 more
wiley   +1 more source

Renal coccidiosis in black skimmers in North America reveals an uncharacterized Eimeria lineage (Apicomplexa: Eimeriidae). [PDF]

PLoS One
Groch KR, Sanders TL, Duran EMI, Clontz D, Grace JK, Rech RR, Verocai GG, Bryan LK.   +7 more
europepmc   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Potassium dichromate induces dose-dependent nephrotoxicity through oxidative stress-mediated downregulation of renal aquaporins and upregulation of KIM-1. [PDF]

Sci Rep
Shehab H, El Sayed IET, Badr EA, Anajirih N, Abdelkader A, ELwakeel EE, Ali NE, Kasem EM, Al-Shahed FAN, Zakari MO, Elmorsy EM, Ibrahim SF, Shukry M, El Nashar EM, Alshehri AM, Rawan AF, Abdeen A.   +16 more
europepmc   +1 more source

Renal Trichodinosis in the Japanese Rice Fish, Oryzias latipes: First Report and Phylogenetic Classification

Journal of Fish Diseases, EarlyView.
ABSTRACT Investigation of a disease outbreak in a hobbyist's medaka (Oryzias latipes) collection led to the detection of Trichodina sp. in the kidney tubuli of individual fish. Based on this observation, a thorough clinical workup, including native microscopy, histopathology and molecular genetics, was conducted.
J. Harl, K. Lipnik, S. Thalguter, E. Lewisch   +3 more
wiley   +1 more source

The IQGAP1-claudin cell junction axis in cisplatin-induced epithelial damage. [PDF]

Cell Commun Signal
Barudi Y, Fan X, Jenkins KW, Dey SK, Dworkin L, Yakirevich E, Osman MA.   +6 more
europepmc   +1 more source

Immunogenicity and Protective Efficacy of the First Autogenous Aeromonas hydrophila Vaccine for Piaractus brachypomus

Journal of Fish Diseases, EarlyView.
ABSTRACT Aeromonas hydrophila is a major zoonotic bacterial pathogen responsible for haemorrhagic septicemia, substantial economic losses in aquaculture and increasing antimicrobial resistance among field isolates. It is also one of the main bacterial species associated with mortality outbreaks in pirapitinga, Piaractus brachypomus, culture in the ...
Layana Aparecida Batista Pereira, Juliana do Nascimento Ferreira, Laine Patricia Costa dos Santos, Larissa Andréia Ferreira Sampaio, Igor Bartolomeu Alves de Barros, Elizabeth Gusmão Affonso, Jefferson Yunis‐Aguinaga, Gustavo da Silva Claudiano   +7 more
wiley   +1 more source

Correction to "Neonatal Hyperoxia Downregulates Claudin-4, Occludin, and ZO-1 Expression in Rat Kidney Accompanied by Impaired Proximal Tubular Development". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

Novel roles of GPCRs in the renal collecting duct. [PDF]

Physiology (Bethesda)
Kui MK, Zhang JJ, Pluznick JL.
europepmc   +1 more source

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai, Thomas Forbes, Simon A. Carter, Alison L. Kent, Chanel Prestidge, David T. Selewski, Eveline Staub, Anke Raaijmakers   +7 more
wiley   +1 more source