Results 11 to 20 of about 19,523 (216)

Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney

open access: yesNature Communications, 2022
How the distal nephron is patterned during kidney development has been difficult to study. Here they show that AP-2β is required for the formation and postnatal function of distal convoluted tubules, whereas AP-2α has a role in maintaining the structure ...
Joseph O. Lamontagne   +7 more
doaj   +1 more source

Disturbances in Switching between Canonical and Non-Canonical Wnt Signaling Characterize Developing and Postnatal Kidneys of Dab1−/− (yotari) Mice

open access: yesBiomedicines, 2023
This study aims to determine the protein expression patterns of acetylated α-tubulin, inversin, dishevelled-1, Wnt5a/b, and β-catenin in developing (E13.5 and E15.5) and early postnatal (P4 and P14) kidneys of Dab1−/− (yotari) mice, their role in ...
Ilija Perutina   +8 more
doaj   +1 more source

Differential expression of KCNQ1 K+ channel in tubular cells of frog kidney

open access: yesEuropean Journal of Histochemistry, 2010
The aim of this study was to evaluate KCNQ1 K+ channel expression in the frog kidney of Rana esculenta. KCNQ1 K+ channel, also known as KvLQT1, is the pore forming a-subunit of the IKs K+ channel, a delayed rectifier voltage-gated K+ channel, which has ...
S. Ćirović   +7 more
doaj   +1 more source

Determination of the dynamic cellular transcriptional profiles during kidney development from birth to maturity in rats by single-cell RNA sequencing

open access: yesCell Death Discovery, 2021
Recent single-cell RNA sequencing (scRNA-seq) analyses have offered much insight into the gene expression profiles in early-stage kidney development. However, comprehensive gene expression profiles from mid- and late-stage kidney development are lacking.
Fangrui Ding   +4 more
doaj   +1 more source

Has exogenous melatonin induce histological changes in collecting tubules and ducts of rat's kidney?

open access: yesمجله كليه طب الكندي, 2022
Back ground; Selective re-absorption and secretion are the functions of the collecting tubules and ducts, in addition to concentrate urine through ADH-regulated and ADH-independent water channels.Method; twenty four male rats were used, they were ...
Mustafa Mohammed Ibraheem   +2 more
doaj  

Immunohistochemical determination of calbindin-d28k in the kidney of postnatal rats

open access: yesVeterinární Medicína, 2004
The localization of calbindin-D28k was examined in rat kidney at different stages of development. Calbindin was found specifically in the distal convoluted tubules (DCT).
S. Timurkaan, B. G Tarakci
doaj   +1 more source

Bellini duct carcinoma

open access: yesAutopsy and Case Reports, 2021
The modern era has brought an appreciation that renal cell carcinoma (RCC) includes diverse subtypes derived from the various parts of the nephron, each with its distinctive genetic basis and tumor biology.
Gil Falcão   +3 more
doaj  

DEVELOPMENTAL STUDIES ON THE KIDNEYS OF RABBITS [PDF]

open access: yesVeterinary Medical Journal - Giza, 2002
The development of the rabbit’s kidney was investigated during the pre and postnatal periods. The bilateral mesonephroi appeared in 11 days old fetuses as two masses bulging into the coclomic cavity; one on either side of the developing aorta.
S GHARBAWY
doaj   +1 more source

In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration

open access: yesCell Reports, 2014
The mechanism and magnitude by which the mammalian kidney generates and maintains its proximal tubules, distal tubules, and collecting ducts remain controversial.
Yuval Rinkevich   +14 more
doaj   +1 more source

Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney

open access: yesFrontiers in Molecular Biosciences, 2022
Background: Several members of the SLC26A family of transporters, including SLC26A3 (DRA), SLC26A5 (prestin), SLC26A6 (PAT-1; CFEX) and SLC26A9, form multi-protein complexes with a number of molecules (e.g., cytoskeletal proteins, anchoring or adaptor ...
Jie Xu   +12 more
doaj   +1 more source

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