Results 31 to 40 of about 31,502 (210)

Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney

Frontiers in Molecular Biosciences, 2022
Background: Several members of the SLC26A family of transporters, including SLC26A3 (DRA), SLC26A5 (prestin), SLC26A6 (PAT-1; CFEX) and SLC26A9, form multi-protein complexes with a number of molecules (e.g., cytoskeletal proteins, anchoring or adaptor ...
Jie Xu, Jie Xu, Sharon Barone, Sharon Barone, Sharon Barone, Mujan Varasteh Kia, L. Shannon Holliday, Kamyar Zahedi, Kamyar Zahedi, Kamyar Zahedi, Manoocher Soleimani, Manoocher Soleimani, Manoocher Soleimani   +12 more
doaj   +1 more source

Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis [PDF]

, 2018
We sought to decipher the mechanisms underlying the kidney's response to changes in K+ load and intake, under physiological and pathophysiological conditions.
Edwards, Aurelie, Layton, Anita T., Vallon, Volker   +2 more
core   +1 more source

Endogenous retinoic acid activity in principal cells and intercalated cells of mouse collecting duct system.

PLoS ONE, 2011
BackgroundRetinoic acid is the bioactive derivative of vitamin A, which plays an indispensible role in kidney development by activating retinoic acid receptors.
Yuen Fei Wong, Jeffrey B Kopp, Catherine Roberts, Peter J Scambler, Yoshifusa Abe, Alexandra C Rankin, Neelanjana Dutt, Bruce M Hendry, Qihe Xu   +8 more
doaj   +1 more source

Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]

, 2017
Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
core   +1 more source

Expression of metallothionein in renal tubules of rats exposed to acute and endurance exercise.

Folia Histochemica et Cytobiologica, 2006
The induction of exercise-induced apoptosis in not actively involved in exercise organs, such as kidney could be a result of oxidative stress. Metallothionein (MT) exerts a protective effect in the cell against oxidative stress and apoptosis.
Katia Rossini, Zbigniew Jethon, Marek Cegielski, Małgorzata Dumańska, Barbara Dolińska-Krajewska, Piotr Dziegiel, Marzena Podhorska-Okołów, Ugo Carraro, Maciej Zabel   +8 more
doaj   +1 more source

Expression and distribution of HIF-1α, HIF-2α, VEGF, VEGFR-2 and HIMF in the kidneys of Tibetan sheep, plain sheep and goat

Folia Morphologica, 2020
BACKGROUND: The objective of this study was to detect the expression and distribution characteristics of five proteins (the hypoxia-inducible factor 1alpha [HIF-1a], HIF-2a, vascular endothelial growth factor [VEGF], VEGF-2 receptor [VEGFR-2] and hypoxia-
K. Yang, Z. Zhang, Y. Li, S. Chen, W. Chen, H. Ding, Z. Tan, Z. Ma, Z. Qiao   +8 more
doaj   +1 more source

Cell volume regulation in the proximal tubule of rat kidney proximal tubule cell volume regulation [PDF]

, 2017
We developed a dynamic model of a rat proximal convoluted tubule cell in order to investigate cell volume regulation mechanisms in this nephron segment.
Edwards, Aurelie, Layton, Anita T.
core   +1 more source

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari, A AntonySunil, A Makino, A Turano, Anindita Das, AO Phillips, B Ashokkumar, B Dutta, B Sihag, BR Chamberlain, CME Tallaksen, Daniel Zehnder, ED Schleicher, Fang Zhang, G Gastaldi, GLJ Page, Guerman Molostvov, H Lum, H Smithline, HM Said, I Hubatsch, J Rieck, James R. Larkin, JC Reidling, JC Reidling, JC Reidling, JD Eudy, KA Robinson, Lisa Godfrey, MJ Boulware, MJ Ryan, MW Pfaffl, N Rabbani, N Rabbani, N Takahashi, N Tasevska, Naila Rabbani, Paul J. Thornalley, PJ Thornalley, R Babaei-Jadidi, S Sander, SM Nabokina, VS Subramanian   +42 more
core   +2 more sources

Minimal Kidney Disease Phenotype in Heterozygous Null Mice

Canadian Journal of Kidney Health and Disease, 2023
Background: Shroom family member 3 (SHROOM3) encodes an actin-associated protein that regulates epithelial morphology during development. Several genome-wide association studies (GWAS) have identified genetic variances primarily in the 5’ region of ...
Allison Lawlor, Kristina Cunanan, Joanna Cunanan, Amy Paul, Hadiseh Khalili, Doyun Ko, Ahsan Khan, Robert Gros, Thomas Drysdale, Darren Bridgewater   +9 more
doaj   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L., Brown, S.G.A., Davern, K.M., Jacoby-Alner, T.E., Stephens, N., Swindells, K.   +5 more
core   +2 more sources