Summary: Human pluripotent stem cells (hPSCs) hold great promise for understanding kidney development and disease. We reproducibly differentiated three genetically distinct wild-type hPSC lines to kidney precursors that underwent rudimentary ...
Ioannis Bantounas +11 more
doaj +1 more source
Microscopy with ultraviolet surface excitation for rapid slide-free histology. [PDF]
Histologic examination of tissues is central to the diagnosis and management of neoplasms and many other diseases, and is a foundational technique for preclinical and basic research.
Bishop, John +10 more
core +2 more sources
Objective: In this study ,the effects of silver nanoparticles (Ag NPs)were investigated on the liver and kidney tissues. Methodology: The produced nanoparticles have an average particle size of about 30 nm. Eighteen male albino rats were used by dividing
Baghdad Science Journal
doaj +1 more source
Overexpression of G-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acids. [PDF]
The cytochrome P450 epoxygenase-dependent arachidonic acid metabolites, epoxyeicosatrienoic acids (EETs), are potent survival factors and mitogens for renal epithelial cells, but the molecular identity in the cells that initiates the mitogenic signaling ...
Seong Kwon Ma +5 more
doaj +1 more source
Ultrastructure of the reproductive system of the black swamp snake (\u3ci\u3eSeminatrix pygaea\u3c/i\u3e). Part III. The sexual segment of the male kidney. [PDF]
In mature male snakes and lizards, a distal portion of the nephron is hypertrophied in relation to its appearance in females and immature males. This sexual segment of the male kidney apparently provides seminal fluid that is mixed with sperm and ...
Sever, David M.
core +1 more source
Centrosome amplification disrupts renal development and causes cystogenesis [PDF]
International ...
Amanda Knoten +79 more
core +8 more sources
Continuous growth of proximal tubular kidney epithelial cells in hormone-supplemented serum-free medium. [PDF]
An epithelial cell line from pig kidney (LLC-PK1) with properties of proximal tubular cells can be maintained indefinitely in hormone-supplemented serum-free medium. Continuous growth requires the presence of seven factors: transferrin, insulin, selenium,
Chuman, L +3 more
core
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro [PDF]
PKD2 is mutated in 15% of patients with autosomal dominant polycystic kidney disease (ADPKD). Polycystin-2 (PC2), the PKD2 protein, is a nonselective Ca2 + -permeable cation channel which may function at the cell surface and ER. Nevertheless, the factors
Kane, M.E. +4 more
core +2 more sources
Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development. [PDF]
Metanephrogenesis has been a long-standing model to study cell-matrix interactions. A number of adhesion molecules, including matrix receptors (i.e., integrins), are believed to be involved in such interactions.
Kanwar, YS +6 more
core
Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet [PDF]
AIM:To determine the effect of tempol in normal rats fed high salt on arterial pressure and the balance between antagonist components of the renal renin-angiotensin system.METHODS:Sprague-Dawley rats were fed with 8% NaCl high-salt (HS) or 0.4% NaCl ...
Cao, Gabriel Fernando +7 more
core +1 more source

