Results 71 to 80 of about 18,819 (193)

Differential role of planar cell polarity gene Vangl2 in embryonic and adult mammalian kidneys.

PLoS ONE, 2020
Planar cell polarity (PCP) pathway is crucial for tissue morphogenesis. Mutations in PCP genes cause multi-organ anomalies including dysplastic kidneys.
Ida Derish, Jeremy K H Lee, Melanie Wong-King-Cheong, Sima Babayeva, Jillian Caplan, Vicki Leung, Chloe Shahinian, Michel Gravel, Michael R Deans, Philippe Gros, Elena Torban   +10 more
doaj   +1 more source

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Medullary sponge kidney presenting in a neonate with distal renal tubular acidosis and failure to thrive: a case report

Journal of Medical Case Reports, 2009
Introduction Medullary sponge kidney is a congenital anomaly characterized by diffuse ectasy of the collecting tubules of one or both kidneys. It is usually diagnosed in the second or third decade of life.
El-Sawi Mohamed, Shahein Abdul-Rahman
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Metastatic collecting duct carcinoma of the kidney treated with sunitinib

World Journal of Surgical Oncology, 2011
Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive malignant tumor arising from the distal collecting tubules which has been shown to have a poor response to several kinds of systemic therapy.
M'rabti Hind, Ahellal Youness, Tazi Mohamed, Essadi Ismail, Tazi El, Errihani Hassan   +5 more
doaj   +1 more source

Species-specific histological characterizations of renal tubules and collecting ducts in the kidneys of cats and dogs

PLOS ONE
The histomorphological features of normal kidneys in cats and dogs have been revealed despite the high susceptibility of cats to tubulointerstitial damage. Herein, the histological characteristics of the two species were compared. Cytoplasmic lipid droplets (LDs) were abundant in the proximal convoluted tubules (PCTs) of cats aged 23–27 months but ...
Shunnosuke Kira, Takashi Namba, Masaya Hiraishi, Teppei Nakamura, Yuki Otani, Yasuhiro Kon, Osamu Ichii   +6 more
openaire   +2 more sources

MORPHO-CYTOLOGICAL STUDY OF THE HEAD, BODY AND CAUDAL PARTS OF KIDNEY IN JUVENILE ACIPENSER PERSICUS USING MODELING METHOD

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2011
Morpho-cytological patterns of juvenile Acipenser persicus on basis of structure, size and distribution of kidney nephrons were studied. Sampling of head, body and caudal parts of the kidney in the fish aged 1 and 2 years were carried out (3 specimens of
S.Olaadi,
doaj  

Disrupted glucocorticoid receptor cell signalling causes a ciliogenesis defect in the fetal mouse renal tubule

EMBO Reports
Primary cilia are cell signalling and environment sensing organelles and have important roles during embryogenesis and homeostasis. We demonstrate glucocorticoid signalling is essential for normal cilia formation in mouse and human renal tubules.
Kelly L Short, Jianshen Lao, Rachel Lam, Julie L M Moreau, Judy Ng, Mehran Piran, Alexander N Combes, Denny L Cottle, Timothy J Cole   +8 more
doaj   +1 more source

Improvement effects of transplanting pancreatic islet that previously incubated with biomaterials on the diabetic nephropathy in STZ- diabetic rats

BMC Nephrology
Background Islet transplantation is an effective treatment for diabetes or even its complications. Aim of this study is to investigate efficacy of biomaterial treated islet transplantation on treating diabetic nephropathy. Methods Male rats were randomly
Marzieh Nemati, Zahra Hosseinzadeh, Fatemeh Nemati, Farhad Koohpeyma   +3 more
doaj   +1 more source