Results 131 to 140 of about 73,145 (294)

Renal function impairment in children with intestinal failure receiving parenteral nutrition: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure are at risk for kidney dysfunction; however, the contributing factors are not well established. We aimed to describe risk factors associated with glomerular and tubular renal dysfunction in children with intestinal failure.
Amanda M. Braga da Mata, Heitor Pons Leite, Eduardo F. Hatanaka, Mariana Janiques Barcia Magalhães Fonseca, Marta Liliane de Almeida Maia, Giovana S. G. Sabio, Maria Fernanda C. de Camargo, Paulo C. Koch Nogueira   +7 more
wiley   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM, Rindler, MJ, Saier, MH, Shaffer, L   +3 more
core  

Systematic Deciphering of ATBC Nephrotoxicity Mechanisms via Machine Learning and Single‐Cell Analysis

Medicine Bulletin, EarlyView.
This study elucidates the nephrotoxic mechanism of acetyl tributyl citrate (ATBC) by integrating network toxicology, machine learning, and single‑cell multi‑omics analysis to systematically decipher the molecular mechanisms and cell‑type‑specific regulatory networks underlying ATBC‑induced kidney injury. First, a protein‑protein interaction network was
Yimao Wu, Yalun Liang, Jintao Liang, Wenlong Sun, Qian Zhang, Meng‐Yao Li   +5 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Proximal convoluted tubules of the rats kidney--a stereological analysis

Bosnian Journal of Basic Medical Sciences, 2003
Background and Purpose: The aim of this work was to order quantitative parameters of the proximal convoluted tubules (PCT) in the normal rat kidney cortex. Volume density (VV), both surface and specific surface density toward interstitium (SVi and SVi/VV) and toward lumen (SVl and SVl/VV) and thickness (T) of tubules epithelium have been ...
openaire   +3 more sources

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

Solvent drag measurement of transcellular and basolateral membrane NaCl reflection coefficient in kidney proximal tubule. [PDF]

, 1991
The NaCl reflection coefficient in proximal tubule has important implications for the mechanisms of near isosmotic volume reabsorption. A new fluorescence method was developed and applied to measure the transepithelial (sigma NaClTE) and basolateral ...
Fushimi, K, Shi, LB, Verkman, AS
core  

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source

Elevated beta‐hydroxybutyrate within a pediatric population and its associated pathology: A retrospective case series

Journal of Forensic Sciences, EarlyView.
Abstract Elevated beta‐hydroxybutyrate (BHB) is a marker for ketoacidosis. Post‐mortem values for the diagnosis of fatal ketoacidosis and the associated clinical and histologic findings are limited in the pediatric population. A retrospective case series of pediatric autopsy records and histology slides was conducted.
Nasim Haghandish, Anthea Girdwood, Christopher Milroy, Jacqueline Parai   +3 more
wiley   +1 more source

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht, Baran Ogurlu, Silke S. M. Wolfswinkel, Henri G. D. Leuvenink, Cyril Moers   +4 more
wiley   +1 more source