Results 151 to 160 of about 85,860 (310)
Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury [PDF]
Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine-glycine-aspartic acid (RGD)-binding integrins are important mediators of the pro-fibrotic response by activating latent TGF-β at sites of injury and ...
Basta, Jeannine+5 more
core +1 more source
The cellular localization of retinol-binding protein (RBP) messenger RNA (mRNA) in the kidney, and the developmental pattern of the renal expression of the RBP gene, were studied in the Sprague-Dawley rat.
A Makover+3 more
doaj
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli+3 more
wiley +1 more source
HATs: Hierarchical Adaptive Taxonomy Segmentation for Panoramic Pathology Image Analysis [PDF]
Panoramic image segmentation in computational pathology presents a remarkable challenge due to the morphologically complex and variably scaled anatomy. For instance, the intricate organization in kidney pathology spans multiple layers, from regions like the cortex and medulla to functional units such as glomeruli, tubules, and vessels, down to various ...
arxiv
In this study, we used bioinformatics and in vitro and in vivo validations to discover the close association of Fosb with AKI, which was significantly upregulated in AKI. Furthermore, Fosb promoted apoptosis through AP‐1 signaling pathway‐mediated inflammatory responses in renal tubular epithelial cells, suggesting that it has the potential to be a ...
Xiaoyan Tang+3 more
wiley +1 more source
C-arm Tomographic Imaging Technique for Nephrolithiasis and Detection of Kidney Stones [PDF]
In this paper, we investigated a C-arm tomographic technique as a new three dimensional (3D) kidney imaging method for nephrolithiasis and kidney stone detection over view angle less than 180o. Our C-arm tomographic technique provides a series of two dimensional (2D) images with a single scan over 40o view angle.
arxiv
Clinical implications of proximal tubular multicilia in glomerular diseases [PDF]
Introduction: Multiciliated cells (MCCs) have been identified in the proximal tubules of patients with kidney disease; however, their clinical significance is unknown. We aimed to investigate whether MCCs are associated with clinical outcomes in patients
Kim B+10 more
europepmc +1 more source
ABSTRACT The percomorph fish clade Gobioidei is a suborder that comprises over 2200 species distributed in nearly all aquatic habitats. To understand the genetics underlying their species diversification, we sequenced and annotated the genome of the loach goby, Rhyacichthys aspro, an early‐diverging group, and compared it with nine additional Gobioidei
Tzi‐Yuan Wang+10 more
wiley +1 more source
Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation. [PDF]
Inflammation is a major cause of morbidity and mortality in Western societies. Despite use of multiple drugs, both chronic and acute inflammation still represent major health burdens.
Amarnath, Venkataraman+10 more
core
Distribution of Galactose-N Acetyl Galactoseamine on the surface of adult mice kidney cells
Background&Objective: Carbohydrate chains link to glycoproteins and glycolipids of the cell surface particulary their terminal sugars have key roles in cellular activities of almost all biological systems.
H.Mofidpour (Ph.D)+3 more
doaj