Results 151 to 160 of about 85,860 (310)

Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury [PDF]

open access: yes, 2020
Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine-glycine-aspartic acid (RGD)-binding integrins are important mediators of the pro-fibrotic response by activating latent TGF-β at sites of injury and ...
Basta, Jeannine   +5 more
core   +1 more source

Localization of retinol-binding protein messenger RNA in the rat kidney and in perinephric fat tissue.

open access: yesJournal of Lipid Research, 1989
The cellular localization of retinol-binding protein (RBP) messenger RNA (mRNA) in the kidney, and the developmental pattern of the renal expression of the RBP gene, were studied in the Sprague-Dawley rat.
A Makover   +3 more
doaj  

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

open access: yesVeterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli   +3 more
wiley   +1 more source

HATs: Hierarchical Adaptive Taxonomy Segmentation for Panoramic Pathology Image Analysis [PDF]

open access: yesarXiv
Panoramic image segmentation in computational pathology presents a remarkable challenge due to the morphologically complex and variably scaled anatomy. For instance, the intricate organization in kidney pathology spans multiple layers, from regions like the cortex and medulla to functional units such as glomeruli, tubules, and vessels, down to various ...
arxiv  

Network expression analysis identifies and experimentally validates the involvement of Fosb in acute kidney injury

open access: yesFASEB BioAdvances, Volume 7, Issue 4, April 2025.
In this study, we used bioinformatics and in vitro and in vivo validations to discover the close association of Fosb with AKI, which was significantly upregulated in AKI. Furthermore, Fosb promoted apoptosis through AP‐1 signaling pathway‐mediated inflammatory responses in renal tubular epithelial cells, suggesting that it has the potential to be a ...
Xiaoyan Tang   +3 more
wiley   +1 more source

C-arm Tomographic Imaging Technique for Nephrolithiasis and Detection of Kidney Stones [PDF]

open access: yesarXiv, 2017
In this paper, we investigated a C-arm tomographic technique as a new three dimensional (3D) kidney imaging method for nephrolithiasis and kidney stone detection over view angle less than 180o. Our C-arm tomographic technique provides a series of two dimensional (2D) images with a single scan over 40o view angle.
arxiv  

Clinical implications of proximal tubular multicilia in glomerular diseases [PDF]

open access: yesHeliyon
Introduction: Multiciliated cells (MCCs) have been identified in the proximal tubules of patients with kidney disease; however, their clinical significance is unknown. We aimed to investigate whether MCCs are associated with clinical outcomes in patients
Kim B   +10 more
europepmc   +1 more source

Chromosome‐Level Genome Assembly of the Loach Goby Rhyacichthys aspro Offers Insights Into Gobioidei Evolution

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT The percomorph fish clade Gobioidei is a suborder that comprises over 2200 species distributed in nearly all aquatic habitats. To understand the genetics underlying their species diversification, we sequenced and annotated the genome of the loach goby, Rhyacichthys aspro, an early‐diverging group, and compared it with nine additional Gobioidei
Tzi‐Yuan Wang   +10 more
wiley   +1 more source

Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation. [PDF]

open access: yes, 2019
Inflammation is a major cause of morbidity and mortality in Western societies. Despite use of multiple drugs, both chronic and acute inflammation still represent major health burdens.
Amarnath, Venkataraman   +10 more
core  

Distribution of Galactose-N Acetyl Galactoseamine on the surface of adult mice kidney cells

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2004
Background&Objective: Carbohydrate chains link to glycoproteins and glycolipids of the cell surface particulary their terminal sugars have key roles in cellular activities of almost all biological systems.
H.Mofidpour (Ph.D)   +3 more
doaj  

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