Results 101 to 110 of about 127,828 (193)

Automatic detection of calcium phosphate deposit plugs at the terminal ends of kidney tubules. [PDF]

Healthc Technol Lett, 2019
Fernandez K, Korinek M, Camp J, Lieske J, Holmes D.   +4 more
europepmc   +1 more source

Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Naturally occurring fragments of collagen type I alpha 1 chain (COL1A1) have been previously associated with chronic kidney disease (CKD), with some fragments showing positive and others negative associations. Using urinary peptidome data from healthy individuals (n = 1131) and CKD patients (n = 5585) this aspect was investigated in detail ...
Ioanna K. Mina, Luis F. Iglesias‐Martinez, Matthias Ley, Lucas Fillinger, Paul Perco, Justyna Siwy, Harald Mischak, Vera Jankowski   +7 more
wiley   +1 more source

Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery. [PDF]

EBioMedicine, 2018
Benedetti V, Brizi V, Guida P, Tomasoni S, Ciampi O, Angeli E, Valbusa U, Benigni A, Remuzzi G, Xinaris C.   +9 more
europepmc   +1 more source

The Role of Magnesium in Liver Cirrhosis

Portal Hypertension &Cirrhosis, EarlyView.
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng, Xudan Wang, He Qi, Hongtao Tang, Xun Qi   +4 more
wiley   +1 more source

RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus. [PDF]

Kidney Int, 2019
Sung CC, Chen L, Limbutara K, Jung HJ, Gilmer GG, Yang CR, Lin SH, Khositseth S, Chou CL, Knepper MA.   +9 more
europepmc   +1 more source

Controlling Drug Release From Supramolecular Polymer Surfaces by a Click‐To‐Release Reaction

Journal of Polymer Science, EarlyView.
We present a strategy combining reactive supramolecular additives with a covalent click‐to‐release reaction for localized drug delivery. A trans‐cyclooctene additive releases a cytotoxic drug upon tetrazine administration. Fluorescent monitoring confirms release, and cytotoxic tests show effective cancer cell death.
Maritza M. Rovers, Joyce E. P. Brouns, Fenna W. B. Craenmehr, Marc Robillard, Joris W. Peeters, Henk M. Janssen, Patricia Y. W. Dankers   +6 more
wiley   +1 more source

Bioengineered kidney tubules efficiently excrete uremic toxins. [PDF]

Sci Rep, 2016
Jansen J, Fedecostante M, Wilmer MJ, Peters JG, Kreuser UM, van den Broek PH, Mensink RA, Boltje TJ, Stamatialis D, Wetzels JF, van den Heuvel LP, Hoenderop JG, Masereeuw R.   +12 more
europepmc   +1 more source

Deep learning (DL)‐based advancements in prostate cancer imaging: Artificial intelligence (AI)‐based segmentation of 68Ga‐PSMSA PET for tumor volume assessment

Precision Radiation Oncology, EarlyView.
This review highlights the use of 68Ga‐PSMA PET in prostate cancer (PC) for tumor volume quantification, crucial for staging, treatment planning, and prognosis. Traditional manual segmentation methods are time‐consuming and variable, while AI‐based segmentation techniques, particularly deep learning models like convolutional neural networks, offer ...
Sharjeel Usmani, Khulood Al Riyami, Subash Kheruka, Shah P Numani, Rashid al Sukaiti, Maria Ahmed, Nadeem Pervez   +6 more
wiley   +1 more source

Kidney tubules: intertubular, vascular, and glomerular cross-talk. [PDF]

Curr Opin Nephrol Hypertens, 2016
Ferenbach DA, Bonventre JV.
europepmc   +1 more source

Nrf2‐Mediated Ferroptosis Is Involved in Berberine‐Induced Alleviation of Diabetic Kidney Disease

Phytotherapy Research, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is the most common and serious complication of diabetes mellitus. Currently, there is a lack of safe and effective preventive strategies for DKD. The study aimed to explore the preventive effects and potential mechanisms of berberine (BBR) against DKD.
Kun Gao, Yunhua Liu, Kun Li, Lin Liu, Yanmo Cai, Xinxue Zhang, Zongjiang Zhao   +6 more
wiley   +1 more source