Results 171 to 180 of about 137,673 (303)

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

Organ Medicine, EarlyView.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source

AI models for automated segmentation of engineered polycystic kidney tubules. [PDF]

Sci Rep
Monaco S, Bussola N, Buttò S, Sona D, Giobergia F, Jurman G, Xinaris C, Apiletti D.   +7 more
europepmc   +1 more source

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

Organ Medicine, EarlyView.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai, Yuanyue Guan, Shiwei Cui, Yuan Gao, Zhipeng Zhao, Rui Li, Li Song, Xiuying Zhao, Runqing Li   +8 more
wiley   +1 more source

A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury. [PDF]

Am J Pathol
Yu SM, King E, Fribourg M, Hartzell S, Tsou L, Gee L, D'Agati VD, Thurman JM, He JC, Cravedi P.   +9 more
europepmc   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Author Correction: AI models for automated segmentation of engineered polycystic kidney tubules. [PDF]

Sci Rep
Monaco S, Bussola N, Buttò S, Sona D, Giobergia F, Jurman G, Xinaris C, Apiletti D.   +7 more
europepmc   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

From Rare Disorders of Kidney Tubules to Acute Renal Injury: Progress and Prospective. [PDF]

Kidney Dis (Basel)
Li J, Hou F, Lv N, Zhao R, Zhang L, Yue C, Nie M, Chen L.   +7 more
europepmc   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source