Results 151 to 160 of about 620,224 (255)

The lipidome of the kidney tubules of ob/ob mice is affected at the infralesional level. [PDF]

Cell Death Discov
Cheval L, Sampaio JL, Poindessous V, Crambert G, Pallet N.   +4 more
europepmc   +1 more source

Redox‐Associated Renal and Male Reproductive Alterations Following Dexamethasone Exposure in Male Rats: Histopathological and Spermatological Evaluations

Journal of Applied Toxicology, EarlyView.
ABSTRACT Dexamethasone (DEX) is widely used in clinical practice, although it may also cause oxidative stress–related damage in different tissues, including the kidney and male reproductive system. This study investigated DEX‐induced renal and reproductive injury in rats and evaluated the modulatory effect of reduced glutathione on DEX‐associated redox
Caner Öztürk, Neşe Hayat Aksoy, Erkan Özkan, Ayşe Ikinci Keleş, Ahmet Karabulut   +4 more
wiley   +1 more source

Protocol for isolating murine kidney tubules and ex vivo cell death assays. [PDF]

STAR Protoc
Belavgeni A, Maremonti F, Linkermann A.
europepmc   +1 more source

Deep Learning‐Assisted Classification of Urinary Red Blood Cell Morphology for Glomerular Hematuria Screening: A Pilot Study

Journal of Clinical Laboratory Analysis, EarlyView.
This retrospective pilot study developed a YOLOv5l‐based deep learning system to detect and classify urinary red blood cells as isomorphic, dysmorphic, or unknown in urine sediment images. The model achieved a precision of 0.84, recall of 0.69, and F1‐score of 0.76 for dysmorphic RBCs, while sample‐level morphology scoring showed preliminary ...
Yih‐Lon Lin, Jung‐Sheng Chen, Ya‐Fan Chuang, Siang‐Ru Huang, Chien‐Sen Liao   +4 more
wiley   +1 more source

AI models for automated segmentation of engineered polycystic kidney tubules. [PDF]

Sci Rep
Monaco S, Bussola N, Buttò S, Sona D, Giobergia F, Jurman G, Xinaris C, Apiletti D.   +7 more
europepmc   +1 more source

Protective Effects of Riociguat Against Contrast‐Induced Nephropathy: An Experimental and Machine Learning‐Based Study in Rats

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Contrast‐induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riociguat, a soluble guanylate cyclase stimulator, in an experimental rat model of CIN and explored machine ...
Mustafa Begenc Tascanov, Kenan Toprak, Sibel Turedi, İsmail Koyuncu, Zulkif Tanrıverdi, Necip Fazıl Dedeoglu, Halil Fedai, Asuman Bicer, İbrahim Halil Altıparmak, Recep Demirbag, Gencay Sarıısık   +10 more
wiley   +1 more source

A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury. [PDF]

Am J Pathol
Yu SM, King E, Fribourg M, Hartzell S, Tsou L, Gee L, D'Agati VD, Thurman JM, He JC, Cravedi P.   +9 more
europepmc   +1 more source

Galectin-3 protects distal convoluted tubules in rhabdomyolysis-induced kidney injury

<jats:title>Abstract</jats:title><jats:p>Advanced glycation endproducts (AGEs) contribute to cellular damage of various pathologies, including kidney diseases.
Czopek, Claudia S., Rosenberger, Christian, Fähling, Michael, Kulow, Vera A., Labes, Robert   +4 more
core   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Author Correction: AI models for automated segmentation of engineered polycystic kidney tubules. [PDF]

Sci Rep
Monaco S, Bussola N, Buttò S, Sona D, Giobergia F, Jurman G, Xinaris C, Apiletti D.   +7 more
europepmc   +1 more source