Results 141 to 150 of about 137,673 (303)

Beyond the Glomerulus—Kidney Tubule Markers and Diabetic Kidney Disease Progression [PDF]

Kidney International Reports, 2021
Bullen, Alexander L., Garimella, Pranav S.   +1 more
openaire   +2 more sources

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Can formaldehyde exposure induce histopathologic and morphometric changes on rat kidney? [¿la exposición al formaldehído puede inducir cambios histopatológicos y morfométricos sobre el riñón de rata?] [PDF]

, 2009
Formaldehyde is used traditionally for fixing the cadaver, and vaporized during dissection and practical studying on cadaver. This study was designed to determine the histopathologic and morphometric changes of rat kidney while all of the experiments ...
Azarhoush, R., Davarian, A., Fazeli, S.A., Ghafari, S., Golalipour, M.J.   +4 more
core  

Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis

Interdisciplinary Medicine, EarlyView.
Discovery and validation of a urinary extracellular vesicle protein signature for the diagnosis of renal allograft fibrosis. Abstract Interstitial fibrosis is the best indicator of irreversible or ongoing renal injury after kidney transplantation and faces considerable diagnostic challenges.
Wenxuan Zhao, Yang Xu, Yuewen Wang, Shihao Jin, Wenhui Wang, Zeming Yu, Yanwen Zhang, Yuxin Zhang, Deling Kong, Bing Wang, Zhenzhou Wu, Jie Zhao, Yuebing Wang   +12 more
wiley   +1 more source

Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation

Scientific Reports
Acute kidney injury (AKI) can progress to chronic kidney disease (CKD), via a mechanism that is still largely unknown. We previously reported that glucosylceramide (GlcCer) acts as a damage-associated molecular pattern (DAMP) during AKI.
Akinori Osada, Miyako Tanaka, Yuki Sugiura, Xunmei Yuan, Shinji Yamashita, Kozue Ochi, Hiro Kohda, Ayaka Ito, Shiori Go, Tetsuya Okajima, Kenji Kadomatsu, Motoko Yanagita, Kazuhiro Furuhashi, Shoichi Maruyama, Takayoshi Suganami   +14 more
doaj   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis [PDF]

, 1990
Expression of the Lactate Dehydrogenase (LDH) genes during various stages of spermatogenesis was studied by using a combination of Northern blot analyses and in situ hybridization techniques.
Bellvé, Anthony, Del Mazo, Jesus, Eversole, Pam, Hiraoka, Yukihiro, Li, Steven S. L., Simon, Melvin, Thomas, Kelwyn   +6 more
core  

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

The importance of proinflammatory failed-repair tubular epithelia as a predictor of diabetic kidney disease progression

iScience
Summary: The immense public health burden of diabetic kidney disease (DKD) has led to an increase in research on the pathophysiology of advanced DKD.
Aya Tomita-Yagi, Natsuko Ozeki-Okuno, Noriko Watanabe-Uehara, Kazumi Komaki, Minato Umehara, Hiroko Sawada-Yamauchi, Atsushi Minamida, Yasuto Sunahara, Yayoi Matoba, Itaru Nakamura, Tomohiro Nakata, Kunihiro Nakai, Tomoharu Ida, Noriyuki Yamashita, Michitsugu Kamezaki, Yuhei Kirita, Takuya Taniguchi, Eiichi Konishi, Satoaki Matoba, Keiichi Tamagaki, Tetsuro Kusaba   +20 more
doaj   +1 more source