Results 161 to 170 of about 88,063 (262)

MECHANISM AND SITES OF HORMONE ACTION IN KIDNEY TUBULES [PDF]

Quarterly Journal of Experimental Physiology, 1982
openaire   +2 more sources

Soluble Immune Checkpoints and Anti‐HLA Antibodies in Kidney Transplant Recipients: Associations With Kidney Function

Immunology, EarlyView.
Soluble immune checkpoints, anti‐HLA panel‐reactive antibodies, and kidney function parameters were evaluated to investigate their associations with early graft function. Pre‐transplant patients showed higher levels of sCD25, sPD‐L1, sTIM‐3, Gal‐9, sCD27, and sPD‐L2 than healthy controls, while post‐transplant temporal changes were observed in sCD25 ...
Cemil Pehlivanoğlu, Fırat Demircan, Başak Aru, Süheyla Apaydın, Abdullah Demir, Rabia Tığlı, Gürkan Tellioğlu, Ali Osman Gürol, Gülderen Yanıkkaya Demirel   +8 more
wiley   +1 more source

Melatonin Receptor 1 and Melatonin Receptor 2 Expression During Human Kidney Development and Their Association with CAKUT. [PDF]

J Dev Biol
Schmitt AK, Tjora V, Kelam N, Gunjača MJ, Todorović P, Picard C, Loche-Dalmon M, Vukojević K, Racetin A.   +8 more
europepmc   +1 more source

The first decade of Kidney International: treasure hunt for the kidney tubule

Kidney International, 2020
openaire   +3 more sources

USP30 inhibits wound healing in diabetic foot ulcers by promoting TRAF6‐induced ferroptosis and angiogenesis inhibition

Journal of Diabetes Investigation, EarlyView.
High glucose upregulates USP30 in HUVECs, which deubiquitinates and stabilizes TRAF6. Stabilized TRAF6 suppresses GPX4 and SLC7A11, increases ROS/MDA/lipid peroxidation, and activates ferroptosis and apoptosis, leading to impaired angiogenesis and delayed wound healing.
Jingjing Yuan, Shuang Sui, Zhenghua Yang, Kaiwen Zhang, Qiang Hu   +4 more
wiley   +1 more source

In vivo and molecular docking investigation of the novel anti-inflammatory and mitochondrial mechanisms underlying the renoprotective effects of resmetirom and curcumin in gentamicin-induced renal toxicity in rats. [PDF]

BMC Nephrol
Ahmed AS, Sabra MS, Shaltout ES, Abdelqader ZS.   +3 more
europepmc   +1 more source

The miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell injury in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Suppression of miR‐145‐5p alleviates DN‐associated renal tissue damage by inhibiting NRF2/SLC7A11‐mediated ferroptosis of RTECs. ABSTRACT Purpose This study aimed to investigate the molecular mechanism by which the miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN ...
Ganlin Wu, Yu Fang, Meirong Xu, Zuopeng Lu, Yu Cao, Yana Gao   +5 more
wiley   +1 more source

Pierson syndrome with numerous dilated tubules masquerading as autosomal recessive polycystic kidney disease: a case report. [PDF]

CEN Case Rep
Yamamura-Miyazaki N, Michigami T, Okamoto N, Iida T, Yanagi K, Kaname T, Fukuda S, Baba M, Fujiwara K, Kubota T.   +9 more
europepmc   +1 more source

Renal Trichodinosis in the Japanese Rice Fish, Oryzias latipes: First Report and Phylogenetic Classification

Journal of Fish Diseases, EarlyView.
ABSTRACT Investigation of a disease outbreak in a hobbyist's medaka (Oryzias latipes) collection led to the detection of Trichodina sp. in the kidney tubuli of individual fish. Based on this observation, a thorough clinical workup, including native microscopy, histopathology and molecular genetics, was conducted.
J. Harl, K. Lipnik, S. Thalguter, E. Lewisch   +3 more
wiley   +1 more source

Induction of fibrosis in human kidney organoids delineates mechanisms and therapeutic targets of fibrotic kidney disease. [PDF]

Stem Cell Res Ther
Doeser MC, Raimann J, Beuke M, Kilcan Z, Menke AF, Klinkhammer BM, Boor P, Schöler HR, Pavenstädt H.   +8 more
europepmc   +1 more source