Results 181 to 190 of about 88,063 (262)

The IQGAP1-claudin cell junction axis in cisplatin-induced epithelial damage. [PDF]

Cell Commun Signal
Barudi Y, Fan X, Jenkins KW, Dey SK, Dworkin L, Yakirevich E, Osman MA.   +6 more
europepmc   +1 more source

Human placental extract ameliorates methotrexate-induced nephrotoxicity in albino rats: ultrastructural, biochemical and biophysical studies. [PDF]

Sci Rep
Mahran HA, Gawaan YM, El-Gerbed MS, Khedr YI.   +3 more
europepmc   +1 more source

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

Experimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source

Kidney angiopoietin-like protein 4 regulates fibrotic responses in diabetic kidney disease. [PDF]

Front Pharmacol
Srivastava SP, Arora AV, Hamed M, Urval A, Dupati A, Xia S, Yoshida S, Inoki K.   +7 more
europepmc   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Spatial transcriptomics identifies IL-32 as a lipid droplet-associated cytokine linked to tubular injury in human diabetic kidney disease. [PDF]

Inflamm Res
Meadows K, Chung H, Vo S, Imanzadeh A, Seo H, Belay SG, Swamy A, Teo W, Chapman K, Andonegui G, Benediktsson H, Stys PK, Pham T, Muruve DA, Chun J.   +14 more
europepmc   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Deciphering the Impact of RAC1-SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models. [PDF]

Adv Sci (Weinh)
Kuraoka S, Higashi Y, Saito S, Pourgonabadi S, Honjoh H, Ishigaki S, Harris PC, Satlin LM, Yamashita M, Morizane R.   +9 more
europepmc   +1 more source

The Reabsorption of Water in the Tubules of the Kidney

Proceedings of the Imperial Academy, 1926
openaire   +2 more sources

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source