Results 51 to 60 of about 137,673 (303)

Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF [PDF]

, 2019
学位記番号 ...
Nakasatomi, Masao, ナカサトミ, マサオ, 中里見, 征央   +2 more
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The Role of Black Soybean and Purple Sweet Potato Active Compound on Advanced Glycation End-Product in Streptozotocin-Induced Type 2 Diabetes Mellitus Rat

Journal of Tropical Life Science, 2019
Diabetic nephropathy is one of the diabetes complications attacking kidney leading to kidney damage. Hyperglycemia accompanying DM causes the increase of Ad-vanced Glycation End-Product (AGE) and Receptor Advanced Glycation End-Product (RAGE) activity ...
Abdul Gofur, Siti Nur Arifah, Yuslinda Annisa, Agung Witjoro, Mochammad Fitri Atho'illah, Sri Rahayu Lestari   +5 more
doaj   +1 more source

Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium

Cell & Bioscience, 2022
Background The kidneys require vast amounts of mitochondria to provide ample energy to reabsorb nutrients and regulate electrolyte, fluid, and blood pressure homeostasis.
Yapei Yuan, Huan Chen, Sihua Ou, Baomei Cai, Ruifang Zhang, Yue Qin, Mengjie Pan, Shangtao Cao, Duanqing Pei, Fan Fan Hou   +9 more
doaj   +1 more source

An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ [PDF]

, 2012
Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are ...
Agmon Y, Armulik A, Bogle RG, Bratosin D, C. Crawford, C. Sprott, C.M. Peppiatt-Wildman, Crawford C, Cupples WA, Dahlstrom A, Dietrich HH, Dunn KW, Hall AM, Hamilton NB, Holliger C, Horiuchi T, Hughes S, J. Munday, Jans D, Kawamura H, L. Sawbridge, Landis EM, MacPhee PJ, Mattson DL, Mattson DL, O’Connor PM, Pallone TL, Pallone TL, Pallone TL, Pallone TL, Pallone TL, Park F, Patzak A, Peppiatt CM, Praetorius HA, R.J. Unwin, Rhinehart K, Rhinehart KL, Roman RJ, S.S.P. Wildman, Shepro D, Silldorff EP, Silldorff EP, Silldorff EP, Sprague RS, T. Desai, T. Kennedy-Lydon, Thiel G, Whitehouse T, Wu DM, Zhang Z, Zhang Z   +51 more
core   +2 more sources

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Morfometría de cortes histológicos de los túbulos renales normales en una muestra de humanos adultos

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Fundamento: los túbulos renales normales se han descrito por morfometría, lo que permite “reconstruir” en tercera dimensión la forma y el tamaño del espécimen estudiado.Objetivo: caracterizar la magnitud de los túbulos renales normales en humanos adultos,
Miosotis de Lourdes Fernández Lastre, Iraldo Mederos Pérez, Yardelys Rego Juhe, Sandor Varela Iraola, Tamara Caraballoso Recio   +4 more
doaj  

Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo [PDF]

, 2013
Cyclic AMP (cAMP) is a ubiquitous second messenger that regulates a variety of essential processes in diverse cell types, functioning via cAMP-dependent effectors such as protein kinase A (PKA) and/or exchange proteins directly activated by cAMP (EPAC ...
Akbari, Baillie, Beyenbach, Beyenbach, Bos, Bos, Bos, Brand, Börner, Cabrero, Chepurny, Coast, Coast, Coast, Coast, Dames, Davies, Day, de Rooij, Dow, Dow, Dow, Dow, Enserink, Evans, Gloerich, Guo, Hallows, Hector, Iijima–Ando, Johnson, Johnson, Kalderon, Kandel, Kaufmann, Kaupp, Kerr, Laroche–Joubert, MacPherson, O'Donnell, O'Donnell, Parks, Pastor–Soler, Pastor–Soler, Poulsen, Radford, Rein, Rosay, Ryu, Ryu, Schröder–Lang, Stierl, Stokman, Sözen, Terhzaz, Terhzaz, Torrie, Weissenberger, Wong, Zaccolo, Zaccolo   +60 more
core   +1 more source

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, EarlyView.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

Study of pathological changes of kidney associated with some diseases in broilers [PDF]

Iraqi Journal of Veterinary Sciences, 2011
Seventy kidney samples of broiler chickens 3-6 weeks old were collected from private chicken farms in Mosul province, used to study gross and histopathological changes in the kidneys.
H. Kh. Ismail, M. Z. Mahmood
doaj