Results 71 to 80 of about 620,224 (255)
Advanced Science, EarlyView.ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Deep-learning model for evaluating histopathology of acute renal tubular injury
Scientific ReportsTubular injury is the most common cause of acute kidney injury. Histopathological diagnosis may help distinguish between the different types of acute kidney injury and aid in treatment.
Thi Thuy Uyen Nguyen +7 more
doaj +1 more source
Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]
, 1990 Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U. +5 more
core +1 more source
Advanced Science, EarlyView.D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen +11 more
wiley +1 more source
Morphological Description and Histological Structure of Kidney in Barn Owl Tyto alba
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 The morphological description and histological structure of Kidney in barn owl Tyto alba have been invesigated. The results of present study revealed that barn owl has pair of elongated solid kidney situated symmetrically on both sides of vertebral ...
Isrra A. A. Khadhim, Hussain A. Dauod
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Advanced Science, EarlyView.TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang +8 more
wiley +1 more source
Ouabain-insensitive, Na-ATPase activity in pure suspensions of rat kidney proximal tubules [PDF]
, 1990 The present work was undertaken to evaluate the distribution of the Na-ATPase activity in the different components of the rat kidney cortex. Suspensions of glomeruli, proximal and distal tubules were prepared following a collagenase digestion of ...
Proverbio, Fulgencio +9 more
core +1 more source
Advanced Science, EarlyView.A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa +6 more
wiley +1 more source
Biomanufacturing of Kidney Organoids, Perfusable Proximal Tubules, and Kidney Tissues
Human kidneys are vital organs that filter blood, regulate electrolyte homeostasis, and produce urine. These complex processes are carried out by nephron subunits composed of glomeruli and tubular segments that are responsible for filtration and ...
Aceves, Jeffrey
core +4 more sources
Distribution of Galactose-N Acetyl Galactoseamine on the surface of adult mice kidney cells
مجله دانشگاه علوم پزشکی گرگان, 2004 Background&Objective: Carbohydrate chains link to glycoproteins and glycolipids of the cell surface particulary their terminal sugars have key roles in cellular activities of almost all biological systems.
H.Mofidpour (Ph.D) +3 more
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