Results 81 to 90 of about 31,728 (253)

Lactococcus garvieae as a Novel Pathogen in Cultured Pufferfish (Takifugu obscurus) in China

Fishes
In October 2023, a disease outbreak in pufferfish (Takifugu obscurus) farms in Zhongshan City, Guangdong, China, caused high mortality. Diseased fish (mean length: 15 ± 1 cm) exhibited swimming disorders, fin rot, hemorrhage, and an enlarged spleen ...
Ruilong Xu, Zhongning He, Yiyang Deng, Yihao Cen, Zequan Mo, Xueming Dan, Yanwei Li   +6 more
doaj   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Preoperative and postoperative imaging as a surgical strategy and feedback on abdominal aortic aneurysm with horseshoe kidney: Case report

SAGE Open Medical Case Reports
A 77-year-old man was diagnosed with an infrarenal abdominal aortic aneurysm coexisting with a horseshoe kidney detected on a computed tomography (CT) scan.
Shizuko Iwasa, Takeshi Katsube, Azumi Hamasaki   +2 more
doaj   +1 more source

Assessing Change in Stone Burden on Baseline and Follow-Up CT: Radiologist and Radiomics Evaluations

Journal of Imaging
This retrospective diagnostic accuracy study compared radiologist-based qualitative assessments and radiomics-based analyses with an automated artificial intelligence (AI)–based volumetric approach for evaluating changes in kidney stone burden on follow ...
Parisa Kaviani, Matthias F. Froelich, Bernardo Bizzo, Andrew Primak, Giridhar Dasegowda, Emiliano Garza-Frias, Lina Karout, Anushree Burade, Seyedehelaheh Hosseini, Javier Eduardo Contreras Yametti, Keith Dreyer, Sanjay Saini, Mannudeep Kalra   +12 more
doaj   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

RENTREN. Nuevo sistema de autoentrenamiento para el manejo de riñones artificiales RENTREN. New self-training system for the use of artificial kidneys

Medisan, 2012
La hemodiálisis es el proceder que permite mantener con vida a los pacientes con insuficiencia renal crónica terminal y se realiza a través de un riñón artificial. La necesidad de unidades nefrológicas más cerca de los lugares donde residen los afectados,
Tania Chaveco Martínez, Juan Ramón Chaveco Martínez   +1 more
doaj  

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Harnessing Artificial Intelligence for Enhanced Renal Analysis: Automated Detection of Hydronephrosis and Precise Kidney Segmentation

European Urology Open Science
Background and objective: Hydronephrosis is essential in the diagnosis of renal colic. We automated the detection of hydronephrosis from ultrasound images to standardize the therapy and reduce the misdiagnosis of renal colic.
Radu Alexa, Jennifer Kranz, Rafael Kramann, Christoph Kuppe, Ritabrata Sanyal, Sikander Hayat, Luis Felipe Casas Murillo, Turkan Hajili, Marco Hoffmann, Matthias Saar   +9 more
doaj   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source