Results 1 to 10 of about 71,763 (262)

The Species-Specific Acquisition and Diversification of a K1-like Family of Killer Toxins in Budding Yeasts of the Saccharomycotina.

PLoS Genetics, 2021
Killer toxins are extracellular antifungal proteins that are produced by a wide variety of fungi, including Saccharomyces yeasts. Although many Saccharomyces killer toxins have been previously identified, their evolutionary origins remain uncertain given
Lance R Fredericks, Mark D Lee, Angela M Crabtree, Josephine M Boyer, Emily A Kizer, Nathan T Taggart, Cooper R Roslund, Samuel S Hunter, Courtney B Kennedy, Cody G Willmore, Nova M Tebbe, Jade S Harris, Sarah N Brocke, Paul A Rowley   +13 more
doaj   +2 more sources

Acquisition of Ly49 Receptor Expression by Developing Natural Killer Cells [PDF]

Journal of Experimental Medicine, 1998
The formation of the repertoire of mouse natural killer (NK) cell receptors for major histocompatibility complex (MHC) class I molecules was investigated by determining the developmental pattern of Ly49 receptor expression. During the first days after birth, few or no splenic NK cells express Ly49A, Ly49C, Ly49G2, or Ly49I receptors.
Jeffrey Dorfman, David Raulet, Raulet David H   +2 more
exaly   +5 more sources

Killer acquisitions no setor financeiro brasileiro?

Revista de Defesa da Concorrência
Contexto: nos últimos anos, a digitalização e a inovação tecnológica transformaram os principais setores da economia e revolucionaram a forma como os consumidores interagem com produtos e serviços.
Luiz Felipe de Abreu, José Gustavo Féres, Eduardo Ribeiro   +2 more
doaj   +2 more sources

Effective allogeneic natural killer cell therapy for pancreatic adenocarcinoma avails conserved activating receptors and evades HLA I-driven inhibition [PDF]

Journal for ImmunoTherapy of Cancer
Background At diagnosis, ~80% of pancreatic ductal adenocarcinomas (PDAC) have metastasized. Relapse is thus common even among patients who undergo surgical resection, the only curative option.
Stacey N Lee, Riley J Arseneau, Thomas Arnason, Jeanette E Boudreau   +3 more
doaj   +2 more sources

Capturing Killer Acquisitions in Digital Markets Under the European Union Merger Control Rules

Trento Student Law Review, 2023
A few years ago, a novel development identified as “Killer Acquisitions” surfaced within the domain of EU Merger Control: incumbent undertakings were under suspicion of acquiring promising startups with the intent of eliminating prospective market ...
Amil Jafarguliyev
doaj   +1 more source

Disentangling Natural and Anthropogenic Forms of Mortality and Serious Injury in a Poorly Studied Pelagic Dolphin

Frontiers in Marine Science, 2021
Killer whale (Orcinus orca) populations specialize in both prey and prey acquisition tactics around the world and may be a primary evolutionary driver of the habits of small cetaceans.
Erin Ashe, Rob Williams, Alexandra Morton, Philip S. Hammond   +3 more
doaj   +1 more source

Killer Acquisitions [PDF]

Journal of Political Economy, 2018
This paper argues incumbent firms may acquire innovative targets solely to discontinue the target’s innovation projects and preempt future competition. We call such acquisitions “killer acquisitions.” We develop a model illustrating this phenomenon. Using pharmaceutical industry data, we show that acquired drug projects are less likely to be developed ...
Cunningham, C M, Ederer, F, Ma, S
openaire   +1 more source

A redox-based characterization of human immune cell subsets by polychromatic flow cytometry

STAR Protocols, 2023
Summary: Cellular redox state determinants are traditionally studied using fluorescent microscopy and immunoblot analysis; however, no procedure has been developed for simultaneous measurement in various immune cell subsets.
Christina Pitsillidou, Ivan Muradore, Elena Pontarini, Milena Bertolotti, Alessandra Roberto   +4 more
doaj   +1 more source

KILLER ACQUISITIONS AND BEYOND: POLICY EFFECTS ON INNOVATION STRATEGIES [PDF]

International Economic Review, 2020
AbstractThis article provides a theory of strategic innovation project choice by incumbents and start‐ups which serves as a foundation for the analysis of acquisition policy. We show that, in spite of countervailing incentives on incumbents and entrants, prohibiting acquisitions has a weakly negative overall innovation effect.
Letina, Igor, Schmutzler, Armin, Seibel, Regina   +2 more
openaire   +7 more sources

Measuring trogocytosis between ovarian tumor and natural killer cells

STAR Protocols, 2022
Summary: Trogocytosis is an active transport mechanism by which one cell extracts a plasma membrane fragment with embedded molecules from an adjacent cell in a contact-dependent process leading to the acquisition of a new function.
Antonio Delgado-Gonzalez, Ying-Wen Huang, Ermelinda Porpiglia, Kenyi Donoso, Veronica D. Gonzalez, Wendy J. Fantl   +5 more
doaj   +1 more source