Results 141 to 150 of about 71,763 (262)

<i>LINC02470</i> impairs natural killer cell cytotoxicity by epigenetically targeting the natural cytotoxicity triggering receptor 1. [PDF]

Front Immunol
Shi X, Zhou L, Li M, Wen X, Chen Y, Niu C, Yin Q, Jin H, Hoffman AR, Cui J, Gao S, Hu JF.   +11 more
europepmc   +1 more source

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

Advanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma, Ying Zou, Yao Wang, Huiyan Li, Jinlin Li, Tianfu Liu, Xiaohong Pan   +6 more
wiley   +1 more source

Immunological and clinical predicators for venous thromboembolism in ANCA-associated vasculitis patients: elevated natural killer cells and cardiac involvement. [PDF]

Arthritis Res Ther
Wu R, Fan Y, Bin Z, Jin R, Zhang X, Gao C, Li X, Wang C.   +7 more
europepmc   +1 more source

KILLER ACQUISITIONS: HOW BIG FIRMS QUIETLY KILL STARTUP COMPETITION

Killer acquisitions occur when major companies purchase start up companies with the aim of eliminating any form of future competition and not encouraging innovation. Since competition law essentially aims at the current market impact and turnover limit, start-ups with disruptive potential are more often than not avoidable by regulation.
openaire   +2 more sources

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

Quantitative Analysis of Splenic Natural Killer Cells of Mice Using Imaging Flow Cytometry. [PDF]

Bio Protoc
Amin MN, Mostaq MS, Uddin MB, Liu YY.
europepmc   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

Profound immune suppression and exhaustion characterize refractory mycoplasma pneumoniae pneumonia in children. [PDF]

Front Immunol
Ma X, Wu Y, He F, Yao H, Cao L, Zhu C.
europepmc   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

Advanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao, Dongdong Liu, Haishan Gao, Chenyang Qin, Wen Zhang, Ziyun Lu, Dongxia Tan, Yuxiu Qu, Yusong Liu, Zhiran Zou, Hongtao Yu, Wei Qi   +11 more
wiley   +1 more source

<i>Candida glabrata</i> and the host: a neglected affair. [PDF]

J Med Microbiol
Ghosh M, Raney M, Kaur R.
europepmc   +1 more source