Results 161 to 170 of about 71,763 (262)

Extranodal NK/T-Cell Lymphoma in the Nasal Region Illustrating the Differential Diagnosis of Lesions of the Face. [PDF]

Clin Case Rep
Dias L, Messias H, Zagalo C, Alves C, Esteves G, Gomes P.   +5 more
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Water‐Enabled Ultralong Full‐Color Organic Phosphorescence in Hydrogen‐Bonded Frameworks for 4D Encryption and Bio‐Imaging

Advanced Science, EarlyView.
Water‐induced quenching challenges organic RTP materials, but a counter‐intuitive strategy employs HOF to encapsulate carbonyl guests, where water functions as a structural reinforcer. This achieves water‐enhanced ultralong RTP with full‐color emission (blue to deep red), overcoming intracellular quenching for high‐signal cellular imaging, alongside 4D
Pengcheng Wu, Zenggang Lin, Lu Yang, Weisheng Liu   +3 more
wiley   +1 more source

The <i>in vivo</i> CAR-T paradigm shift-Reflections from Boston and the rise of programmable immunity. [PDF]

Mol Ther Nucleic Acids
Giangrande PH.
europepmc   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

An innovative treatment for lung cancer using gene-engineered human-induced pluripotent stem cell-derived natural killer cells. [PDF]

Cancer Immunol Immunother
Sato Y, Goto K, Yagishita S, Miyata K, Uesugi N, Torisawa YS, Naritomi Y, Takahashi R, Sho R, Takeno Y, Kurachi K, Yamada M, Higashi Y, Kimura H, Hamada A, Nishigaki F, Tamura K.   +16 more
europepmc   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

Longitudinal Dynamics of NK-Cell Regulatory Signaling and IVIG Response in Kawasaki Disease. [PDF]

Children (Basel)
Kim Y, Choi I, Choi KS, Jeong IS, Cho HJ.   +4 more
europepmc   +1 more source

Killer acquisitions : challenges arising under Competition Law

Η τρέχουσα εργασία σκιαγραφεί το θέμα των εξοντωτικών εξαγορών (killer acquisitions), εξετάζοντάς το κυρίως μέσω των αποφάσεων των αρμοδίων αρχών ανταγωνισμού. Αξιολογεί αυτό το φαινόμενο στο πλαίσιο του δικαίου του ανταγωνισμού, το οποίο διαχρονικά ανταποκρίνεται δυναμικά σε διάφορες προκλήσεις και μεταβαλλόμενες συνθήκες κατά περίπτωση, προσπαθώντας ...
openaire   +1 more source

Photothermal Amplification via Nanorobotic Swarming Dynamics

Advanced Science, EarlyView.
This study explores a novel approach to enhance photothermal therapy using magnetically regulated microswarms. It details the development of magnetic nanoparticles organized into dynamic structures that improve heat retention and conversion efficiency.
Qinglong Wang, Lin Su, Zhengxin Yang, Yihang Jiang, Haojin Yang, Qianqian Wang, Li Zhang, Ben Wang, Jiajia Wang   +8 more
wiley   +1 more source