Results 21 to 30 of about 653,047 (312)
Evasion of NK cell immune surveillance via the vimentin-mediated cytoskeleton remodeling
Frontiers in Immunology, 2022 Cancer immunotherapy uses the immune system to achieve therapeutic effects; however, its effect is still limited. Therefore, in addition to immune checkpoint-based treatment, the development of other strategies that can inhibit cancer cells from ...
Jei-Ming Peng +8 more
doaj +1 more source
Latency reversal plus natural killer cells diminish HIV reservoir in vivo
Nature Communications, 2022 HIV is difficult to eradicate due to the persistence of a long-lived reservoir of latently infected cells. Previous studies have shown that natural killer cells are important to inhibiting HIV infection, but it is unclear whether the administration of ...
Jocelyn T. Kim +22 more
semanticscholar +1 more source
Leukemia, 2015 Targeting PD1–PDL1 immune checkpoint in plasmacytoid dendritic cell interactions with T cells, natural killer cells and multiple myeloma ...
A. Ray +6 more
semanticscholar +1 more source
Human natural killer cells: form, function, and development
Journal of Allergy and Clinical Immunology, 2022 Human natural killer (NK) cells are innate lymphoid cells that mediate important effector functions in the control of viral infection and malignancy.
E. Mace
semanticscholar +1 more source
Natural killer cells in cancer biology and therapy
Molecular Cancer, 2020 The tumor microenvironment is highly complex, and immune escape is currently considered an important hallmark of cancer, largely contributing to tumor progression and metastasis.
Song-Yang Wu +3 more
semanticscholar +1 more source
The Role of Natural Killer Cells in Autoimmune Diseases
Frontiers in Immunology, 2021 Natural killer (NK) cells, the large granular lymphocytes differentiated from the common lymphoid progenitors, were discovered in early 1970’s. They are members of innate immunity and were initially defined by their strong cytotoxicity against virus ...
U. Kucuksezer +6 more
semanticscholar +1 more source
Role of Decidual Natural Killer Cells in Human Pregnancy and Related Pregnancy Complications
Frontiers in Immunology, 2021 Pregnancy is a unique type of immunological process. Healthy pregnancy is associated with a series of inflammatory events: implantation (inflammation), gestation (anti-inflammation), and parturition (inflammation).
Xiuhong Zhang, Haiming Wei
semanticscholar +1 more source
SnapShot: Natural Killer Cells
Cell, 2020 NK cells are broadly distributed innate lymphoid cells (ILCs) encompassing distinct populations based on CD11b and CD27 expression in mice or CD56 intensity in humans. Involved in anti-viral and anti-tumor immunity thanks to their cytokines and chemokines secretion as well as their cytotoxic capabilities, NK cells have emerged as a promising ...
Crinier, Adeline +3 more
openaire +3 more sources
Natural Killer Cells in Psoriasis [PDF]
Journal of Innate Immunity, 2011 Psoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-α, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions,
A M, Tobin +3 more
openaire +2 more sources
Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells
Haematologica, 2016 Natural killer cells are key cells of the innate immune system. Natural killer cell receptor repertoires are diversified by a stochastic expression of killer-cell-immunoglobulin-like receptors and lectin-like receptors such as NKG2 receptors.
Loredana Ruggeri +10 more
doaj +1 more source