Results 211 to 220 of about 2,849,925 (342)

When is a lipid kinase not a lipid kinase? When it is a protein kinase

Cell, 1995
openaire   +3 more sources

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Editorial: LRRK2—Fifteen Years From Cloning to the Clinic

Frontiers in Neuroscience, 2022
Hardy Rideout, Elisa Greggio, Arjan Kortholt, Arjan Kortholt, Arjan Kortholt, R. Jeremy Nichols   +5 more
doaj   +1 more source

Exploring the pharmacological action mechanism of chamomile essential oil on the treatment of breast cancer based on network pharmacology. [PDF]

BMC Complement Med Ther
Maitisha G, Zhou J, Zhao Y, Liu G, Zhao Y, Zheng Y, Li L, Han S, Peng L, Abliz A.   +9 more
europepmc   +1 more source

Thymidine Kinase: Evidence for its Absence from Neurospora crassa and Some Other Micro-organisms, and the Relevance of This to the Specific Labelling of Deoxyribonucleic Acid

, 1968
Anthony R. Grivell, J. F. Jackson
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Evaluating the pentapharmacological potency of otamixaban against lung cancer CDK2, transferase, oxidoreductase and signalling proteins. [PDF]

PLoS One
Baeissa HM, Bakhsh T, Shakoori AM, Sindi G, Zaki RM, Kamal MA, Alsufyani HA, Habib AH, Ishaq A Khayyat A, Rafeeq M, Jairajpuri DS.   +10 more
europepmc   +1 more source

Kinetic and Magnetic Resonance Studies of the Pyruvate Kinase Reaction

, 1965
Albert S. Mildvan, Mildred Cohn
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Selective detection of a key region in chemotaxis signaling protein complexes by solid-state NMR. [PDF]

Biophys J
Allen JJ, Wang S, Rienstra CM, Thompson LK.   +3 more
europepmc   +1 more source