Results 281 to 290 of about 3,327,333 (431)

Combination of antiangiogenic and systemic therapy in advanced non-small cell lung cancer: before and after progression to leptomeningeal metastasis. [PDF]

Sci Rep
Zhu XD, Amanjiaoer RH, Shen YL, Li N, Abdurazik MH, Liu CL, Sun G.   +6 more
europepmc   +1 more source

Serum enzyme studies in muscle disease: Part II Serum creatine kinase activity in muscular dystrophy and in other myopathic and neuropathic disorders [PDF]

, 1964
John Pearce, R. J. Pennington, J. N. Walton   +2 more
openalex   +1 more source

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

Current Biology, 1997
D. Alessi, S. James, C. Downes, A. Holmes, P. Gaffney, C. Reese, P. Cohen   +6 more
semanticscholar   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

Cigarette Smoke Exposure Leads to Organic and Mineral Bone Component Changes: The Importance of Rho Kinase Function in These Events. [PDF]

Cells
da Silva AF, Lima FJ, Moreira AR, Silva CDN, de Oliveira IB, Callera AF, Porfirio AL, Alves LHV, Tibério IFLC, Velosa APP, Jorgetti V, Teodoro WR, Lopes FDTQDS.   +12 more
europepmc   +1 more source

Deoxythymidine Kinase of Escherichia coli

, 1964
Reiji Okazaki, Arthur Kornberg
openalex   +1 more source

Deficient activity of dephosphophosphorylase kinase and accumulation of glycogen in the liver [PDF]

, 1969
George Hug, William K. Schubert, Gail Chuck   +2 more
openalex   +1 more source

Targeting the phosphoinositide 3-kinase pathway in cancer

Nature reviews. Drug discovery, 2009
Pixu Liu, Hailing Cheng, T. Roberts, Jean J. Zhao   +3 more
semanticscholar   +1 more source

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

Arthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner, Anna Shmagel, Gerd Horneff, Ivan Foeldvari, Jordi Antón, Athimalaipet V. Ramanan, Yuli Qian, Kristina Unnebrink, Shuai Hao, Heidi S. Camp, Nasser Khan, Wei Liu, Mohamed‐Eslam F. Mohamed   +12 more
wiley   +1 more source

Network pharmacology-based investigation of the pharmacological mechanisms of diosgenin in nonalcoholic steatohepatitis. [PDF]

Sci Rep
Gu P, Chen J, Xin J, Chen H, Zhang R, Chen D, Zhang Y, Shao S.   +7 more
europepmc   +1 more source