Results 31 to 40 of about 147,757 (263)

The Arabidopsis CDPK-SnRK superfamily of protein kinases [PDF]

open access: yes, 2003
The CDPK-SnRK superfamily consists of seven types of serine-threonine protein kinases: calcium-dependent protein kinase (CDPKs), CDPK-related kinases (CRKs), phosphoenolpyruvate carboxylase kinases (PPCKs), PEP carboxylase kinase-related kinases (PEPRKs),
Halford, N   +28 more
core   +1 more source

Nek family of kinases in cell cycle, checkpoint control and cancer [PDF]

open access: yes, 2011
Early studies in lower Eukaryotes have defined a role for the members of the NimA related kinase (Nek) family of protein kinases in cell cycle control. Expansion of the Nek family throughout evolution has been accompanied by their broader involvement in ...
Haider Nasir   +15 more
core   +1 more source

Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance

open access: yesFrontiers in Cellular and Infection Microbiology, 2013
Aminoglycosides are a class of antibiotics with a broad spectrum of antimicrobial activity. Unfortunately, resistance in clinical isolates is pervasive, rendering many aminoglycosides ineffective.
Kun eShi   +4 more
doaj   +1 more source

JNK and ERK8 as downstream effectors of receptor tyrosine kinases [PDF]

open access: yes, 2006
MAP kinases are a super-family of serine-threonine protein kinases expressed in all eukaryotic cells. In mammals, there are many MAP kinases with different biological functions, grouped in distinctly regulated groups, ERK1/2 (extracellular signal related
Iavarone, Carlo
core   +1 more source

Oxidative Stress, Kinase Activation, and Inflammatory Pathways Involved in Effects on Smooth Muscle Cells During Pulmonary Artery Hypertension Under Hypobaric Hypoxia Exposure

open access: yesFrontiers in Physiology, 2021
High-altitude exposure results in hypobaric hypoxia, which affects organisms by activating several mechanisms at the physiological, cellular, and molecular levels and triggering the development of several pathologies.
Patricia Siques   +3 more
doaj   +1 more source

C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis [PDF]

open access: yes, 2003
Understanding the regulation of the apoptotic program in neurons by intracellular pathways is currently a subject of great interest. Recent results suggest that c-Jun N-terminal kinases (JNK), mitogen-activated protein kinases and the transcription ...
Brugg, B.   +4 more
core   +1 more source

How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture [PDF]

open access: yes, 2020
Small molecule kinase inhibitors that stabilize distinct ATP-binding site conformations can differentially modulate the glob-al conformation of Src-family kinases (SFKs). However, it is unclear which specific ATP-binding site contacts are responsible for
Linglan, Fang   +6 more
core   +1 more source

Phylogenetic, structure and expression analysis of ABC1Ps gene family in rice

open access: yesBiologia Plantarum, 2012
The ABC1 protein family (ABC1P), a new family of putative kinases, widely existed in procaryote and eucaryote. A comprehensive genome-wide analysis was carried out in this study to find all ABC1Ps in rice (Oryza sativa subsp. japonica).
S. G. Yang   +6 more
doaj   +1 more source

Kinase Signaling in Dendritic Development and Disease

open access: yesFrontiers in Cellular Neuroscience, 2021
Dendrites undergo extensive growth and remodeling during their lifetime. Specification of neurites into dendrites is followed by their arborization, maturation, and functional integration into synaptic networks.
Kimya Nourbakhsh, Smita Yadav
doaj   +1 more source

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase [PDF]

open access: yes, 2012
eEF2K [eEF2 (eukaryotic elongation factor 2) kinase] phosphorylates and inactivates the translation elongation factor eEF2. eEF2K is not a member of the main eukaryotic protein kinase superfamily, but instead belongs to a small group of so-called ...
Hussain, Nusrat   +16 more
core   +1 more source

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