Results 241 to 250 of about 900,715 (293)

Kinetics of Antibody-Hapten Interactions

1977
The immune system, which is the major defence complex present in vertebrates against foreign cells and pathogens, is comprised of lymphocytes and their products, the antibodies. The latter carry out the function of recognition of antigenic determinants and the resultant triggering of a wide range of biological responses.
I, Pecht, D, Lancet
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Kinetics of the daunomycin-DNA interaction

Biochemistry, 1985
The kinetics of the interaction of daunomycin with calf thymus DNA are described. Stopped-flow and temperature-jump relaxation methods, using absorption detection, were used to study the binding reaction. Three relaxation times were observed, all of which are concentration dependent, although the two slower relaxations approach constant values at high ...
J B, Chaires, N, Dattagupta, D M, Crothers   +2 more
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Kinetics of a carbamazepine-ethosuximide interaction

Clinical Pharmacology and Therapeutics, 1980
Carbamazepine and ethosuximide are used together to treat epileptic mixed-seizure patterns. Since carbamazepine has been shown to induce drug-metabolizing enzyme(s) in the liver, it follows that carbamazepine may alter ethosuximide disposition. Six normal subjects took one 250-mg ethosuximide capsule twice each day for 55 consecutive doses (study days ...
J W, Warren, J D, Benmaman, B B, Wannamaker, R H, Levy   +3 more
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Kinetics of drug-drug interactions

Journal of Pharmacokinetics and Biopharmaceutics, 1973
Open any current medical journal and one is reminded that the coadministration of two or more drugs can either cause deleterious effects or lead to ineffective therapy. Those concerned with drug therapy are increasingly aware of this phenomenon but are confronted with the problem that a patient may be taking three, four, and, on occasion, even more ...
Malcolm Rowland, Shaikh B. Matin
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Kinetic studies of protein–protein interactions

Current Opinion in Structural Biology, 2002
The structure of a protein-protein interaction, its affinity and thermodynamic characteristics depict a 'frozen' state of a complex. This picture ignores the kinetic nature of complex formation and dissociation, which are of major biological and biophysical interest.
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Kinetic simulation of anticancer drug interactions

International Journal of Bio-Medical Computing, 1980
A model is described that simulates the biochemical pathways of folate and nucleotide metabolism involved in DNA precursor biosynthesis. Examples are given of use of the model to study various aspects of the biochemical pharmacology of antitumour drugs.
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Kinetics of atom–photon Interactions

International Journal of Quantum Chemistry, 1995
AbstractIn order to avoid the violation of basic principles of macroscopic reversibility and detailed balance, we propose a cell kinetic model for atom‐photon interactions instead of Enstein's classical photon kinetic mechanism. Our model can be interpreted as a generalization of either mass action law or Einstein's original scheme.
K. Oláh, J. Bódiss
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A kinetic study of protein-protein interactions

Biochemistry, 1976
Kinetic studies have been carried out of the monomer-dimer interaction of insulin, beta-lactoglobulin, and alpha-chymotrypsin using stopped-flow and temperature-jump techniques. The pH indicators bromothymol blue, bromophenol blue, and phenol red were used to monitor pH changes associated with the monomer-dimer interaction. In all three cases a kinetic
R, Koren, G G, Hammes
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Molecular interactions and kinetic properties of fats

Progress in Lipid Research, 1999
This article has reviewed the recent work on the molecular interactions and kinetic properties of the polymorphic transformations of the TAGs in the single and mixed states. Progress has recently been made in the molecular-level understanding of the polymorphic transformations of the TAGs.
K, Sato, S, Ueno, J, Yano
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Kinetic Study of the Cetyltrimethylammonium/DNA Interaction

The Journal of Physical Chemistry B, 2009
A kinetic study of the interaction of the surfactant cetyltrimethylammonium (CTA(+)) with DNA was carried out in water and in salt (NaCl) solutions. The results can be explained in terms of a reaction mechanism involving two consecutive reversible steps. The first step corresponds to the union/separation of the surfactant with/from the DNA.
E, Grueso, E, Roldan, F, Sanchez
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