Results 301 to 310 of about 40,318 (318)
A pivot-tether model for nucleosome recognition by the chromosomal passenger complex
Ruza RR +6 more
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Journal of Cell Science, 2023
ABSTRACT The microtubule minus-end-directed motility of cytoplasmic dynein 1 (dynein), arguably the most complex and versatile cytoskeletal motor, is harnessed for diverse functions, such as long-range organelle transport in neuronal axons and spindle assembly in dividing cells.
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ABSTRACT The microtubule minus-end-directed motility of cytoplasmic dynein 1 (dynein), arguably the most complex and versatile cytoskeletal motor, is harnessed for diverse functions, such as long-range organelle transport in neuronal axons and spindle assembly in dividing cells.
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The kinetochore of the hemiptera
Chromosoma, 1961(1) Breakage of chromosomes was induced by X-rays in adult and nymphal males of Euschistus servus, E. tristigmus and Solubea pugnax (Pentatomidae; Hemiptera-Heteroptera). (2) The diffuse nature of the kinetochore is demonstrated by the ability of chromosome fragments to perpetuate themselves mitotically through many cell generations of ...
Franz Schrader, Sally Hughes-Schrader
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Biochemical Society Transactions, 2006 The Ran GTPase controls many cellular functions, including nucleocytoplasmic trafficking, spindle assembly, nuclear assembly and cell-cycle progression. Considerable evidence suggests that diffusible Ran-GTP near mitotic chromatin facilitates the release of critical factors from nuclear transport receptors, thereby promoting organization of mitotic ...
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Trends in Plant Science, 2000
Kinetochores are large protein complexes that bind to centromeres. By interacting with microtubules and their associated motor proteins, kinetochores both generate and regulate chromosome movement. Kinetochores also function in the spindle checkpoint; a surveillance mechanism that ensures that metaphase is complete before anaphase begins.
Hong-Guo Yu +3 more
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Kinetochores are large protein complexes that bind to centromeres. By interacting with microtubules and their associated motor proteins, kinetochores both generate and regulate chromosome movement. Kinetochores also function in the spindle checkpoint; a surveillance mechanism that ensures that metaphase is complete before anaphase begins.
Hong-Guo Yu +3 more
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Centromeres and kinetochores of Brassicaceae
Chromosome Research, 2014The centromere-the primary constriction of monocentric chromosomes-is essential for correct segregation of chromosomes during mitosis and meiosis. Centromeric DNA varies between different organisms in sequence composition and extension. The main components of centromeric and pericentromeric DNA of Brassicaceae species are centromeric satellite repeats.
Michael Sandmann +2 more
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Spindles and Kinetochores [PDF]
Nature New Biology, 1971 Cellular Mechanisms of Chromosome Distribution by Peter Luykx. (International Review of Cytology, Supplement 2.) Pp. vii+173. (Academic: New York and London, September 1970.) 112s.
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The structure of a primitive kinetochore
Trends in Biochemical Sciences, 1989The isolation of yeast centromeres has provided the opportunity to describe the molecular structure of chromosome attachments to the mitotic spindle. Nucleolytic probes of chromatin structure and construction of conditional mutants in centromere function have been used to study the regulation and assembly of centromeres throughout the cell cycle in ...
Alison Presmanes Hill +3 more
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Nature Cell Biology, 2003
The most interesting discoveries are often those that couple distinct fields of science in unexpected ways. The marriage of the nuclear pore complex to the kinetochore and spindle checkpoint regulation is a recent example, raising the question of why such divergent processes as mitosis and nuclear transport use common proteins.
Ian G. Macara, P. Todd Stukenberg
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The most interesting discoveries are often those that couple distinct fields of science in unexpected ways. The marriage of the nuclear pore complex to the kinetochore and spindle checkpoint regulation is a recent example, raising the question of why such divergent processes as mitosis and nuclear transport use common proteins.
Ian G. Macara, P. Todd Stukenberg
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Kinetochore structure and function
Trends in Cell Biology, 2005The vertebrate kinetochore is a complex structure that specifies the attachments between the chromosomes and microtubules of the spindle and is thus essential for accurate chromosome segregation. Kinetochores are assembled on centromeric chromatin through complex pathways that are coordinated with the cell cycle.
Gordon K. Chan, Song-Tao Liu, Tim J. Yen
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