Results 301 to 310 of about 117,673 (373)

The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore

Cell, 2006
I. Cheeseman, J. Chappie, E. Wilson-Kubalek, A. Desai   +3 more
semanticscholar   +1 more source

False Positive or False Negative—An Interesting Case in Prenatal Diagnostic Laboratory

Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
A prenatal case in which discordant results were identified among SNP‐Array, PNBoBs, conventional karyotyping, and FISH, highlighting the importance of recognizing the limitations of various testing techniques for clinicians to avoid misdiagnosis and missed diagnosis.
Pingping Zhang, Yanmei Sun, Haishen Tian, Xuedong Shi, Limin Rong, Yali Li   +5 more
wiley   +1 more source

A genome-wide RNAi screen for novel CIN genes using human artificial chromosome. [PDF]

PNAS Nexus
Liskovykh M, Kochanova NY, Chiang CY, Dhall A, Aksenova V, Chen YC, Reinhold WC, Dasso M, Thomas A, Cheng KC, Pommier Y, Earnshaw WC, Larionov V, Kouprina N.   +13 more
europepmc   +1 more source

De Novo Truncating Mutations in the Kinetochore-Microtubules Attachment GeneCHAMP1Cause Syndromic Intellectual Disability

, 2016
Bertrand Isidor, Sébastien Küry, Jill A. Rosenfeld, Thomas Besnard, Sébastien Schmitt, Shelagh Joss, Sally Davies, Robert Roger Lebel, Alex Henderson, Christian P. Schaaf, Haley Streff, Yaping Yang, Vani Jain, Nodoka Chida, Xénia Latypova, Cédric Le Caignec, Benjamin Cogné, Sandra Mercier, Marie Vincent, Estelle Colin, Dominique Bonneau, Anne‐Sophie Denommé‐Pichon, Philippe Parent, Brigitte Gilbert‐Dussardier, Sylvie Odent, Annick Toutain, Amélie Piton, Christian Dina, Audrey Donnart, Pierre Lindenbaum, Éric Charpentier, Richard Redon, Kenji Iemura, Masanori Ikeda, Kozo Tanaka, Stéphane Bezieau   +35 more
openalex   +2 more sources

Prenatally Diagnosed 7q11.23 Copy Number Variations: A Retrospective Case Series

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
Prenatal 7q11.23 CNVs exhibit 100% ultrasound anomalies in deletions (cardiovascular defects, growth restriction) and 50% in duplications. Inherited CNVs (50% deletions, 43% duplications) correlate with milder outcomes, while de novo variants drive high TOP rates (76.5%), emphasizing genomic testing and parental studies for precise counseling. ABSTRACT
Jiong Yan, Ziyang Liu, Song Yi, Nian Liu
wiley   +1 more source

Centromeres in the thermotolerant yeast K. marxianus mediate attachment to a single microtubule. [PDF]

Chromosome Res
Barrero DJ, Hedouin S, Mao Y, Asbury CL, Stergachis AB, O'Toole E, Biggins S.   +6 more
europepmc   +1 more source

Structural basis of product recognition by Mycobacterium tuberculosis fatty acid synthase

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Microbial iterative fatty acid synthases (FAS) are versatile multienzymes under scrutiny for their potential as anti‐infectious targets and their biotechnological applications. They produce saturated fatty acids with defined chain length and release them as coenzyme A‐conjugates.
Elnaz Khalili Samani, S M Naimul Hasan, Alexander F. A. Keszei, Mahtab Heydari, Mohammad T. Mazhab‐Jafari   +4 more
wiley   +1 more source

Centromeres drive and take a break. [PDF]

Chromosome Res
Talbert PB, Henikoff S.
europepmc   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida, Kazuki M. Matsuda, Hirohito Kotani, Hayakazu Sumida, Shinichi Sato   +4 more
wiley   +1 more source

Insects evolved a monomeric histone-fold domain in the CENP-T protein family. [PDF]

EMBO Rep
Sankaranarayanan SR, Ulmer J, Mørch A, Ali-Ahmad A, Sekulić N, Drinnenberg IA.   +5 more
europepmc   +1 more source