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The kinetochores of Caenorhabditis elegans
Chromosoma, 1982Light microscopy of the mitotic chromosomes of Caenorhabditis elegans suggests that non-localized kinetochores are present, since the chromosomes appear as stiff rods 1 to 2 micrometers in length and lack any visible constriction. The holokinetic structure was confirmed by reconstructions of electron micrographs of dividing nuclei in serially sectioned
J. Nichol Thomson +2 more
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The Formation, Structure, and Composition of the Mammalian Kinetochore and Kinetochore Fiber
1982Publisher Summary Advances in the understanding of the formation, structure, and chemistry of the mammalian kinetochore and its associated fiber are summarized in the chapter. The initiation of chromosome movement during cell division can be correlated with the formation of a fiber, composed primarily of microtubules (MTs) and associated proteins ...
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Evolving Centromeres and Kinetochores
2017The genetic material, contained on chromosomes, is often described as the "blueprint for life." During nuclear division, the chromosomes are pulled into each of the two daughter nuclei by the coordination of spindle microtubules, kinetochores, centromeres, and chromatin.
Steven Friedman, Michael Freitag
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Kinetochore-Microtubule Interactions
2008Kinetochores are the multiprotein macromolecular assemblies on chromatin that ensure the accurate and timely segregation of chromosomes at duringmitosis. To achieve this, kinetochores must interact with the microtubules of the spindle andmicrotubule-associated proteins.
Clayton, Lesley, Tanaka, Tomoyuki U.
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Kinetochores on the move [PDF]
Nature, 1988 Anthony A. Hyman, Timothy J. Mitchison
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Journal of Cell Biology
A new study by Larson and colleagues (2025. J. Cell Biol.https://doi.org/10.1083/jcb.202405176) reveals that kinetochores are biased to bind to microtubule plus-ends due to an interplay between subcomplex organization and the intrinsic polarity of microtubules.
Christian Cozma, Stefan Westermann
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A new study by Larson and colleagues (2025. J. Cell Biol.https://doi.org/10.1083/jcb.202405176) reveals that kinetochores are biased to bind to microtubule plus-ends due to an interplay between subcomplex organization and the intrinsic polarity of microtubules.
Christian Cozma, Stefan Westermann
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Kinetochore attachment sensed by competitive Mps1 and microtubule binding to Ndc80C
Science, 2015Zhejian Ji, Haishan Gao, Hongtao Yu
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Kinetochore assembly and function through the cell cycle
Chromosoma, 2016Harsh Nagpal, T. Fukagawa
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Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN).
Progress in molecular and subcellular biology, 2017Masatoshi Hara, T. Fukagawa
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