Kinetoplastida: new therapeutic strategies [PDF]
New formulations and therapeutic switching of the established drugs, amphotericin B and paromomycin, together with the discovery of miltefosine, have significantly improved the opportunities for treatment of visceral leishmaniasis (VL) chemotherapy ...
Croft S.L.
doaj +4 more sources
TriTrypDB: An integrated functional genomics resource for kinetoplastida.
Parasitic diseases caused by kinetoplastid parasites are a burden to public health throughout tropical and subtropical regions of the world. TriTrypDB (https://tritrypdb.org) is a free online resource for data mining of genomic and functional data from ...
Achchuthan Shanmugasundram +11 more
doaj +3 more sources
Urban landscapes tend to increase the presence of pathogenic protozoa, microsporidia and viruses, but likely decrease the abundance of viruses in wild bees and wasps. [PDF]
• The bees Anthophora plumipes and Osmia cornuta had a higher occurrence probability of the neogregarine protozoan Apicystis bombi in more fragmented urban areas.• In the bee Halictus scabiosae and wasp Polistes dominula, hotter urban areas increased the likelihood of occurrence of viruses.• The viruses were found to be replicative in the samples, and ...
Ferrari A, Cilia G, Polidori C.
europepmc +2 more sources
More surprises from Kinetoplastida [PDF]
Protozoan parasites of the order Kinetoplastida include various species of the genera Leishmania and Trypanosoma that are responsible for substantial human morbidity and mortality in the tropics. Pathogenic Leishmania species cause a diverse group of diseases, collectively called leishmaniasis, that range in severity from spontaneously healing skin ...
J E, Donelson +2 more
openaire +2 more sources
Trypanosoma cruzi : time for international recognition as a foodborne parasite [PDF]
Leishmaniasis is a complex parasitic disease from a taxonomic, clinical and epidemiological point of view. The role of genetic exchanges has been questioned for over twenty years and their recent experimental demonstration along with the identification ...
Alarcón de Noya, Belkisyolé +4 more
core +9 more sources
Metatranscriptomic analysis of larvae guts from field-collected and laboratory-reared Spodoptera frugiperda from the South American subtropical region [PDF]
This is the first study to report a high-throughput approach integrating gene expression data from Spodoptera frugiperda guts and their associated metatranscriptomes.
Cabrera, Natalia Alina +2 more
core +2 more sources
Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]
Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor +58 more
core +1 more source
Phylogeny of the kinetoplastida: taxonomic problems and insights into the evolution of parasitism
To further investigate phylogeny of kinetoplastid protozoa, the sequences of small subunit (18S) ribosomal RNA of nine bodonid isolates and ten isolates of insect trypanosomatids have been determined.
Dmitri A Maslov +2 more
doaj +1 more source
Mitogenome sequence of a Black Sea isolate of the kinetoplastid Bodo saltans
We obtained the mitogenome sequence of a Black Sea isolate of the kinetoplastid Bodo saltans. This sequence consists of two contigs totaling 24,925 bp and encodes ten protein-coding genes, one conserved ORF and one rRNA gene.
Romain Gastineau +6 more
doaj +1 more source
The compartmentalization of untranslated mRNA molecules in granules occurring in many eukaryotic organisms including trypanosomatids involves the formation of complexes between mRNA molecules and RNA-binding proteins (RBPs).
Ana Alonso +6 more
doaj +1 more source

