Results 11 to 20 of about 657 (146)

Gas Flow Shaping via Novel Modular Nozzle System (MoNoS) Augments kINPen-Mediated Toxicity and Immunogenicity in Tumor Organoids [PDF]

Cancers, 2023
Medical gas plasma is an experimental technology for anticancer therapy. Here, partial gas ionization yielded reactive oxygen and nitrogen species, placing the technique at the heart of applied redox biomedicine. Especially with the gas plasma jet kINPen, anti-tumor efficacy was demonstrated.
Torsten Gerling, Sander Bekeschus, Lea Miebach   +2 more
exaly   +7 more sources

Concept for Improved Handling Ensures Effective Contactless Plasma Treatment of Patients with kINPen^® MED [PDF]

Applied Sciences, 2020
The nursing of patients with wounds is an essential part of medical healthcare. In this context, cold atmospheric-pressure plasma sources can be applied for skin decontamination and stimulation of wound healing.
Veronika Hahn, Daniel Grollmisch, Hannes Bendt, Thomas von Woedtke, Bodo Nestler, Klaus-Dieter Weltmann, Torsten Gerling   +6 more
doaj   +4 more sources

The spatial density distribution of H₂O₂ in the effluent of the COST-Jet and the kINPen-sci operated with a humidified helium feed gas [PDF]

Plasma Sources Science and Technology, 2023
Abstract Cold atmospheric plasma jets operated with a helium feed gas containing small admixtures of water vapour are excellent sources of H2O2 for direct biomedical applications. However, H2O2 is typically distributed non-uniformly throughout the effluent region, meaning the dosage received by a patient or substrate is dependent on ...
B Harris, L Krös, A S C Nave, E Wagenaars, J H van Helden   +4 more
openaire   +3 more sources

Investigating the Mutagenicity of a Cold Argon-Plasma Jet in an HET-MN Model. [PDF]

PLoS ONE, 2016
OBJECTIVE:So-called cold physical plasmas for biomedical applications generate reactive oxygen and nitrogen species and the latter can trigger DNA damage at high concentrations.
Susanne Kluge, Sander Bekeschus, Claudia Bender, Hicham Benkhai, Axel Sckell, Harald Below, Matthias B Stope, Axel Kramer   +7 more
doaj   +3 more sources

Nitrosylation vs. oxidation - How to modulate cold physical plasmas for biological applications. [PDF]

PLoS ONE, 2019
Thiol moieties are major targets for cold plasma-derived nitrogen and oxygen species, making CAPs convenient tools to modulate redox-signaling pathways in cells and tissues.
Jan-Wilm Lackmann, Giuliana Bruno, Helena Jablonowski, Friederike Kogelheide, Björn Offerhaus, Julian Held, Volker Schulz-von der Gathen, Katharina Stapelmann, Thomas von Woedtke, Kristian Wende   +9 more
doaj   +2 more sources

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

Advanced NanoBiomed Research
Cold medical gas plasma promotes hemostasis through platelet activation, yet the underlying molecular and functional mechanisms remain incompletely understood.
Sander Bekeschus, Broder Poschkamp, Lea Miebach, Anke Schmidt, Linus Hübner, Julia van der Linde   +5 more
doaj   +2 more sources

Gesundheitsökonomische Aspekte der Kaltplasmatherapie: exemplarische Betrachtung der Versorgung chronischer Wunden mithilfe des Plasmajet kINPen MED

Gesundheitsökonomie & Qualitätsmanagement, 2023
Hintergrund Eine chronische Wunde wird als Integritätsverlust der Haut und darunter liegender Strukturen definiert, der trotz sachgerechter Therapie nicht innerhalb von sechs Wochen abheilt. Unabhängig von dieser zeitlichen Definition sollten Wunden, die auf eine chronische Erkrankung mit fortbestehender Ursache für Geschwürentwicklungen, die ...
Witte, J., Gensorowsky, D., Zeitler, A., Greiner, Wolfgang, Strohal, R.   +4 more
openaire   +3 more sources

Active Free Radical Cold Atmosphere Plasma Promotes Healing of Diabetes Foot Ulcer: Mechanism and Challenge. [PDF]

Diabetes Metab Res Rev
ABSTRACT Background Diabetic foot ulcers (DFUs) have become an important cause of disability and death in patients with diabetes. Traditional therapies are prone to problems such as recurrence and drug resistance, which result in unsatisfactory healing effects for DFUs.
Wang Y, Zhang J, Yan J, Bi W, Ma J.
europepmc   +2 more sources

Enhancing PEEK bond strength: the impact of chemical and mechanical surface modifications on surface characteristics and phase transformation [PDF]

BMC Oral Health
Objectives This study investigated the effects of different surface modifications on surface roughness, phase transformation, and bond strength of polyetheretherketone (PEEK) to composite resin. Materials and Methods A total of 140 specimens measuring 10
Emel Arslan, Ipek Caglar
doaj   +2 more sources

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation. [PDF]

Small
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Schmidt A, Heuser M, Schulan P, Miebach L, Martinet A, Frank M, Wende K, Bekeschus S.   +7 more
europepmc   +2 more sources