Results 31 to 40 of about 657 (146)

Combined In Vitro Toxicity and Immunogenicity of Cold Plasma and Pulsed Electric Fields

open access: yesBiomedicines, 2022
In modern oncology, therapies are based on combining monotherapies to overcome treatment resistance and increase therapy precision. The application of microsecond-pulsed electric fields (PEF) is approved to enhance local chemotherapeutic drug uptake ...
Christina M. Wolff   +2 more
doaj   +1 more source

Ex Vivo Exposure of Human Melanoma Tissue to Cold Physical Plasma Elicits Apoptosis and Modulates Inflammation

open access: yesApplied Sciences, 2020
Cutaneous melanoma is the most aggressive type of skin cancer with a not-sufficient clinical outcome. High tumor mutation rates often hamper a remedial treatment, creating the need for palliative care in many patients.
Sander Bekeschus   +8 more
doaj   +1 more source

Conductive Gas Plasma Treatment Augments Tumor Toxicity of Ringer’s Lactate Solutions in a Model of Peritoneal Carcinomatosis

open access: yesAntioxidants, 2022
Reactive species generated by medical gas plasma technology can be enriched in liquids for use in oncology targeting disseminated malignancies, such as metastatic colorectal cancer.
Lea Miebach   +3 more
doaj   +1 more source

Gas Plasma Protein Oxidation Increases Immunogenicity and Human Antigen-Presenting Cell Maturation and Activation

open access: yesVaccines, 2022
Protein vaccines rely on eliciting immune responses. Inflammation is a prerequisite for immune responses to control infection and cancer but is also associated with disease onset.
Ramona Clemen   +3 more
doaj   +1 more source

Gas Plasma-Treated Prostate Cancer Cells Augment Myeloid Cell Activity and Cytotoxicity

open access: yesAntioxidants, 2020
Despite recent improvements in cancer treatment, with many of them being related to foster antitumor immunity, tumor-related deaths continue to be high. Novel avenues are needed to complement existing therapeutic strategies in oncology.
Sander Bekeschus   +5 more
doaj   +1 more source

Elevated H2AX Phosphorylation Observed with kINPen Plasma Treatment Is Not Caused by ROS-Mediated DNA Damage but Is the Consequence of Apoptosis [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2019
Phosphorylated histone 2AX (γH2AX) is a long-standing marker for DNA double-strand breaks (DSBs) from ionizing radiation in the field of radiobiology. This led to the perception ofγH2AX being a general marker of direct DNA damage with the treatment of other agents such as low-dose exogenous ROS that unlikely act on cellular DNA directly.
Sander Bekeschus   +8 more
openaire   +2 more sources

The Anticancer Efficacy of Plasma-Oxidized Saline (POS) in the Ehrlich Ascites Carcinoma Model In Vitro and In Vivo

open access: yesBiomedicines, 2021
Cold physical plasma, a partially ionized gas rich in reactive oxygen species (ROS), is receiving increasing interest as a novel anticancer agent via two modes.
Walison Augusto Silva Brito   +9 more
doaj   +1 more source

Numerical analysis of the effect of nitrogen and oxygen admixtures on the chemistry of an argon plasma jet operating at atmospheric pressure

open access: yesNew Journal of Physics, 2015
In this paper we study the cold atmospheric pressure plasma jet, called kinpen, operating in Ar with different admixture fractions up to 1% pure ${{{\rm N}}_{2}}$ , ${{{\rm O}}_{2}}$ and ${{{\rm N}}_{2}}$ + ${{{\rm O}}_{2}}$ .
W Van Gaens   +5 more
doaj   +1 more source

Cold Physical Plasma-Mediated Fenretinide Prodrug Activation Confers Additive Cytotoxicity in Epithelial Cells

open access: yesAntioxidants, 2023
Cold physical plasma is a partially ionized gas operated at body temperature and utilized for heat-sensitive technical and medical purposes. Physical plasma is a multi-component system consisting of, e.g., reactive species, ions and electrons, electric ...
Mohsen Ahmadi   +7 more
doaj   +1 more source

The Hyaluronan Pericellular Coat and Cold Atmospheric Plasma Treatment of Cells

open access: yesApplied Sciences, 2020
In different tumors, high amounts of hyaluronan (HA) are correlated with tumor progression. Therefore, new tumor therapy strategies are targeting HA production and degradation. In plasma medicine research, antiproliferative and apoptosis-inducing effects
Claudia Bergemann   +3 more
doaj   +1 more source

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