Results 21 to 30 of about 675 (151)

Active Free Radical Cold Atmosphere Plasma Promotes Healing of Diabetes Foot Ulcer: Mechanism and Challenge. [PDF]

Diabetes Metab Res Rev
ABSTRACT Background Diabetic foot ulcers (DFUs) have become an important cause of disability and death in patients with diabetes. Traditional therapies are prone to problems such as recurrence and drug resistance, which result in unsatisfactory healing effects for DFUs.
Wang Y, Zhang J, Yan J, Bi W, Ma J.
europepmc   +2 more sources

Enhancing PEEK bond strength: the impact of chemical and mechanical surface modifications on surface characteristics and phase transformation [PDF]

BMC Oral Health
Objectives This study investigated the effects of different surface modifications on surface roughness, phase transformation, and bond strength of polyetheretherketone (PEEK) to composite resin. Materials and Methods A total of 140 specimens measuring 10
Emel Arslan, Ipek Caglar
doaj   +2 more sources

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation. [PDF]

Small
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Schmidt A, Heuser M, Schulan P, Miebach L, Martinet A, Frank M, Wende K, Bekeschus S.   +7 more
europepmc   +2 more sources

Gas Plasma Exposure Attenuates the Inflammatory Rheumatoid Arthritis-Like Phenotype of Murine Synoviocytes in Vitro. [PDF]

J Cell Mol Med
ABSTRACT Rheumatoid arthritis (RA) is driven by hyperplastic fibroblast‐like synoviocytes (FLS) that adopt a persistent inflammatory and invasive phenotype, often resistant to conventional therapies. Here, we investigated whether cold gas plasma exposure modulates inflammatory FLS (iFLS) in vitro.
Kordt M, Bergmann-Ewert W, Aleith J, Bekeschus S, Müller-Hilke B.   +4 more
europepmc   +2 more sources

Single Cold Atmospheric Plasma Therapy May Improve the Treatment Outcome of Canine Otitis Externa With Secondary Infection. [PDF]

Vet Dermatol
Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Mueller RS, Bouassiba C.
europepmc   +2 more sources

Feasibility and Safety of Argon Cold Plasma Use as an Adjunctive Treatment for Corneal Disease in Dogs, Cats and Small Mammals: A Prospective Clinical Study. [PDF]

Vet Ophthalmol
ABSTRACT Objective Evaluation of the feasibility of argon cold plasma (ACP) use in corneal diseases in clinical practice and assessment of short‐ and long‐term safety in dogs, cats, and small mammals. Animals Studied Client‐owned animals. Procedure ACP was performed in animals with corneal diseases using the kINPenVET (Neoplas GmbH, Germany) under ...
Soukup P, Allgoewer I.
europepmc   +2 more sources

Combined Toxicity of Gas Plasma Treatment and Nanoparticles Exposure in Melanoma Cells In Vitro

Nanomaterials, 2021
Despite continuous advances in therapy, cancer remains a deadly disease. Over the past years, gas plasma technology emerged as a novel tool to target tumors, especially skin. Another promising anticancer approach are nanoparticles.
Sander Bekeschus
doaj   +1 more source

Modeling Gas Plasma-Tissue Interactions in 3D Collagen-Based Hydrogel Cancer Cell Cultures

Bioengineering, 2023
Gas plasma jet technology was recently identified as a potential adjuvant in the fight against cancer. Here, the partial ionization of gas yields the local formation of an exceptional variety of highly reactive oxygen (ROS) and nitrogen (RNS) species ...
Lea Miebach, Marten Hagge, Sander Bekeschus   +2 more
doaj   +1 more source

Medical Gas Plasma Treatment in Head and Neck Cancer—Challenges and Opportunities

Applied Sciences, 2020
Despite progress in oncotherapy, cancer is still among the deadliest diseases in the Western world, emphasizing the demand for novel treatment avenues.
Julia Berner, Christian Seebauer, Sanjeev Kumar Sagwal, Lars Boeckmann, Steffen Emmert, Hans-Robert Metelmann, Sander Bekeschus   +6 more
doaj   +1 more source

Gas Plasma Technology Augments Ovalbumin Immunogenicity and OT‐II T Cell Activation Conferring Tumor Protection in Mice

Advanced Science, 2021
Reactive oxygen species (ROS/RNS) are produced during inflammation and elicit protein modifications, but the immunological consequences are largely unknown.
Ramona Clemen, Eric Freund, Daniel Mrochen, Lea Miebach, Anke Schmidt, Bernhard H. Rauch, Jan‐Wilm Lackmann, Ulrike Martens, Kristian Wende, Michael Lalk, Mihaela Delcea, Barbara M. Bröker, Sander Bekeschus   +12 more
doaj   +1 more source