Results 111 to 120 of about 181,399 (228)

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Centromeric AA motif in KIR as an optimal surrogate marker for precision definition of alloimmune reproductive failure

Scientific Reports
Throughout pregnancy, the decidua is predominantly populated by NK lymphocytes expressing Killer immunoglobulin-like receptors (KIR) that recognize human leukocyte antigen-C (HLA-C) ligands from trophoblast cells.
Raquel Gil Laborda, Edgard Rodríguez de Frías, Nabil Subhi-Issa, Elena Carrillo de Albornoz, Elena Meliá, Marcos Órdenes, Victoria Verdú, Juan Vidal, Esther Suárez, Isabel Santillán, Daniel Ordóñez, David Pintado-Vera, Victoria González Villafáñez, Ángel Lorenzo, Manuel Fariñas, Mario Rodríguez-Paíno, María Núñez Beltrán, Áurea García Segovia, Ainhoa del Olmo, Fernando Martín Cañadas, Rosa Daurelio, Alfonso de la Fuente, José Manuel González Casbas, Vega Cabezuelo, Francisco Ros Berruezo, Miguel Ángel Moreno Hidalgo, Silvia Iniesta, Beatriz Bueno, Álvaro Martínez Acera, Alexandra Izquierdo, José Luis Vicario, Miguel Fernández-Arquero, Silvia Sánchez-Ramón   +32 more
doaj   +1 more source

A Bag-of-Paths Node Criticality Measure

, 2017
This work compares several node (and network) criticality measures quantifying to which extend each node is critical with respect to the communication flow between nodes of the network, and introduces a new measure based on the Bag-of-Paths (BoP ...
Lebichot, Bertrand, Saerens, Marco
core   +1 more source

PLoS One [PDF]

The role of killer cell immunoglobulin-like receptors (KIRs) in the transmission of HIV-1 has not been extensively studied. Here, we investigated the association of KIR gene content polymorphisms with perinatal HIV-1 transmission.

core  

Natural Killer (NK) Cell Alloreactivity in Haploidentical Stem Cell Transplantation

Cells
This paper conducts a literature review on the role of natural killer cells in haploidentical hematopoietic stem cell transplantation. Theoretical concepts related to KIR genes are introduced regarding their structure, nomenclature, genetic organization,
Mar Luis-Hidalgo, José Luis Piñana, Carlos Solano, Dolores Planelles   +3 more
doaj   +1 more source

Comments on Holographic Entanglement Entropy and RG Flows

, 2012
Using holographic entanglement entropy for strip geometry, we construct a candidate for a c-function in arbitrary dimensions. For holographic theories dual to Einstein gravity, this c-function is shown to decrease monotonically along RG flows.
A Adams, A Allais, A Buchel, A Buchel, A Chamblin, A Pakman, A Schwimmer, A Schwimmer, A Sinha, A Sinha, A Zamolodchikov, AD Shapere, Ajay Singh, C Imbimbo, D Anselmi, D Anselmi, D Freedman, D Gaiotto, D Lovelock, D Lovelock, D Mateos, D Poland, DG Boulware, DL Jafferis, DM Hofman, DM Hofman, DV Fursaev, E Barnes, E Gava, E Witten, H Casini, H Casini, H Casini, H Osborn, I Antoniadis, I Gullu, I Low, IR Klebanov, IR Klebanov, IR Klebanov, J Boer de, J Boer de, J Polchinski, J-F Fortin, JL Cardy, K Skenderis, KA Intriligator, L Girardello, L Girardello, L Mezincescu, L-Y Hung, L-Y Hung, L-Y Hung, M Blau, M Brigante, M Brigante, M Buican, M Duff, M Duff, M Headrick, M Henningson, M Henningson, MF Paulos, MF Paulos, O Aharony, O DeWolfe, P Breitenlohner, P Breitenlohner, P Calabrese, P Calabrese, P Calabrese, R Jackiw, R Rattazzi, R-G Cai, R-G Cai, RC Myers, RC Myers, RC Myers, RC Myers, RM Wald, Robert C. Myers, RV Buniy, S Deser, S Dubovsky, S El-Showk, S Hellerman, S Nojiri, S Ryu, S Ryu, SW Hawking, T Albash, T Albash, T Hirata, T Jacobson, T Jacobson, TL Curtright, U Camara, V Iyer, VS Rychkov, X-H Ge, XO Camanho, Z Komargodski   +101 more
core   +1 more source

A higher CD34 + cell dose correlates with better event-free survival after KIR-ligand mismatched cord blood transplantation for childhood acute myeloid leukemia

Journal of Hematology & Oncology
Although killer Ig-like receptor ligands (KIR-L) mismatch has been associated with alloreactive natural killer cell activity and potent graft-versus-leukemia (GVL) effect among adults with acute myeloid leukemia (AML), its role among children with AML ...
Hisashi Ishida, Yuta Kawahara, Daisuke Tomizawa, Yasuhiro Okamoto, Asahito Hama, Yuko Cho, Katsuyoshi Koh, Yuhki Koga, Nao Yoshida, Maho Sato, Kiminori Terui, Naoyuki Miyagawa, Akihiro Watanabe, Junko Takita, Ryoji Kobayashi, Masaki Yamamoto, Kenichiro Watanabe, Keiko Okada, Koji Kato, Kimikazu Matsumoto, Moeko Hino, Ken Tabuchi, Hirotoshi Sakaguchi   +22 more
doaj   +1 more source

K-ATP channel gene expression is induced by urocortin and mediates its cardioprotective effect [PDF]

, 2002
Background-Urocortin is a novel cardioprotective agent that can protect cardiac myocytes from the damaging effects of ischemia/reperfusion both in culture and in the intact heart and is effective when given at reperfusion.Methods and Results-We have ...
Chanalaris, A, Comini, L, Ferrari, R, Hubank, M, Knight, RA, Latchman, DS, Lawrence, KM, Pasini, E, Scarabelli, T, Stephanou, A, Tinker, A, Townsend, PA   +11 more
core  

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes

Frontiers in Immunology
IntroductionAccurate genotyping of Killer cell Immunoglobulin-like Receptor (KIR) genes plays a pivotal role in enhancing our understanding of innate immune responses, disease correlations, and the advancement of personalized medicine.
Qinghui Zhou, Mazyar Ghezelji, Ananth Hari, Ananth Hari, Michael K. B. Ford, Connor Holley, S. Cenk Sahinalp, Ibrahim Numanagić   +7 more
doaj   +1 more source

The combination of anti-KIR monoclonal antibodies with anti-PD-1/PD-L1 monoclonal antibodies could be a critical breakthrough in overcoming tumor immune escape in NSCLC

Drug Design, Development and Therapy, 2018
Yayi He,1,2,* Sangtian Liu,1,* Jane Mattei,3 Paul A Bunn Jr,2 Caicun Zhou,1 Daniel Chan2 1Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai ...
He YY, Liu ST, Mattei J, Bunn Jr PA, Zhou CC, Chan D   +5 more
doaj