Results 91 to 100 of about 16,602 (265)
Kisspeptin regulates the development of caprine primordial follicles in vitro
Journal of Animal Reproduction and Biotechnology, 2021 Kisspeptin, a neuropeptide and the master controller of reproductive axis upstream to GnRH neurons, and its receptor are also expressed in extrahypothalamic tissues, such as ovaries.
Manjula Priyantha Sumith Magamage +4 more
doaj +1 more source
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
, 2016 Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
core +1 more source
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. [PDF]
, 2011 BACKGROUND: Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH.
Allard, Pat +13 more
core +2 more sources
Andrology, Volume 13, Issue 8, Page 2022-2034, November 2025.Abstract Background Hypogonadism and infertility are two conditions that are heavily affected by overweight and obesity in the male patient. Glucagon‐like peptide 1 agonists (GLP‐1RAs) are a recently introduced class of antidiabetic drugs with powerful weight‐loss effect; this may induce an indirect positive effect on the testicular function ...
Gianmaria Salvio +6 more
wiley +1 more source
Kisspeptin/GPR54 System: What Do We Know About Its Role in Human Reproduction?
Cellular Physiology and Biochemistry, 2018 Kisspeptin is involved in the control of human reproduction bridging the gap between the sex steroid levels and feedback mechanisms that control the gonadotropin releasing hormone (GnRH) secretion; however, studies considering this peptide and ...
Camila M. Trevisan +6 more
doaj +1 more source
Follicle size on day of trigger most likely to yield a mature oocyte [PDF]
, 2018 Funding: MRC, BBSRC and NIHR and supported by the NIHR/Wellcome Trust Imperial Clinical Research Facility and Imperial Biomedical Research Centre.Objective: To identify follicle sizes on the day of trigger most likely to yield a mature oocyte following ...
Alexander N. Comninos +12 more
core +3 more sources
Kisspeptin Regulation of Arcuate Neuron Excitability in Kisspeptin Receptor Knockout Mice [PDF]
Endocrinology, 2015 The G protein-coupled receptor 54 (GPR54) is critical for kisspeptin to activate GnRH neurons to modulate fertility. However, the often mismatching distribution of kisspeptin and GPR54 in the brain suggests that kisspeptin may also act on other receptors.
Xinhuai Liu, Allan E. Herbison
openaire +3 more sources
Advanced Science, Volume 12, Issue 38, October 13, 2025.This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang +12 more
wiley +1 more source
Kisspeptin Activates Ankrd 26 Gene Expression in Migrating Embryonic GnRH Neurons
Frontiers in Endocrinology, 2016 Kisspeptin, a newly discovered neuropeptide regulates gonadotropin-releasing hormone (GnRH). Kisspeptins are a large RF-amide family of peptides. The kisspeptin coded by kiss1 gene is a 145-amino acid- protein that is cleaved to C-terminal peptide ...
Tomoko eSoga +3 more
doaj +1 more source
Biology of Reproduction, 2015 The importance of kisspeptin in regulating vertebrate reproduction has been well established, but the exact mechanism continues to unfold. Unlike mammals, many lower vertebrates possess a dual kisspeptin system, Kiss1 and Kiss2. To decipher the roles of the kisspeptins in fish, we identified two potential kisspeptin antagonists, pep 234 and pep 359, by
Nilli Zmora +6 more
openaire +5 more sources