Results 91 to 100 of about 16,997 (262)

Optogenetics studies of kisspeptin neurons

Peptides, 2023
Optical systems and genetic engineering technologies have made it possible to control neurons and unravel neuronal circuit behavior with high temporal and spatial resolution. The application of optogenetic strategies to understand the physiology of kisspeptin neuronal circuits has evolved in recent years among the neuroendocrine community.
Deyana, Ivanova, Kevin T, O'Byrne
openaire   +2 more sources

Hyperalgesic activity of kisspeptin in mice. [PDF]

, 2011
BACKGROUND: Kisspeptin is a neuropeptide known for its role in the hypothalamic regulation of the reproductive axis. Following the recent description of kisspeptin and its 7-TM receptor, GPR54, in the dorsal root ganglia and dorsal horns of the spinal ...
Biagioni, Francesca, Biasiotta, Antonella, Chiechio, Santina, Colledge, William H, Copani, Agata, Cruccu, Giorgio, Nicoletti, Ferdinando, Sortino, Maria Angela, Spampinato, Simona, Trabucco, Angela   +9 more
core   +4 more sources

Changes in Circulating Kisspeptin Levels During Each Trimester in Women With Antenatal Complications [PDF]

, 2021
Ali Abbara, M. Al‐Memar, Maria Phylactou, Elisabeth Daniels, Bijal Patel, Pei Chia Eng, Rans Nadir, Chioma Izzi‐Engbeaya, Sophie Clarke, Edouard Mills, Tia Hunjan, Ewa Pacuszka, Lisa Yang, Paul Bech, Tricia Tan, Alexander Comninos, Tom Kelsey, C. Kyriacou, H. Fourie, T. Bourne, Waljit S. Dhillo   +20 more
openalex   +1 more source

Intra-Testicular Signals Regulate Germ Cell Progression and Production of Qualitatively Mature Spermatozoa in Vertebrates [PDF]

, 2014
Spermatogenesis, a highly conserved process in vertebrates, is mainly under the hypothalamic-pituitary control, being regulated by the secretion of pituitary gonadotropins, FSH and LH, in response to stimulation exerted by Gonadotropin Releasing Hormone (
Gilda Cobellis, Riccardo Pierantoni, Rosanna Chianese, Rosaria Meccariello, Silvia Fasano, Teresa Chioccarelli, Vincenza Ciaramella   +6 more
core   +2 more sources

Exploring the Role of Kisspeptin in Polycystic Ovary Syndrome and Its Associated Pregnancy Complications

Obesity Reviews, Volume 27, Issue 1, Page 1-21, January 2026.
ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang, Xinmeng Sun, Haiyun Guan, Rongmin Wang, Wei Zhang, Hexia Xia   +5 more
wiley   +1 more source

Kisspeptin and seasonality in sheep [PDF]

Peptides, 2009
Sheep are seasonal breeders, experiencing a period of reproductive quiescence during spring and early summer. During the non-breeding period, kisspeptin expression in the arcuate nucleus is markedly reduced. This strongly suggests that the mechanisms that control seasonal changes in reproductive function involve kisspeptin neurons.
Clarke, I.J., Smith, J.T., Caraty, Alain, Goodman, R.L., Lehman, M.N.   +4 more
openaire   +3 more sources

Neuroanatomical evidence that kisspeptin directly regulates isotocin and vasotocin neurons. [PDF]

PLoS ONE, 2013
Neuropeptide kisspeptin has been suggested to be an essential central regulator of reproduction in response to changes in serum gonadal steroid concentrations.
Shinji Kanda, Yasuhisa Akazome, Yuta Mitani, Kataaki Okubo, Yoshitaka Oka   +4 more
doaj   +1 more source

The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. [PDF]

, 2011
BACKGROUND: Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH.
Allard, Pat, Aparicio, Samuel AJ, Burleigh, Angela, Colledge, William H, d'Anglemont de Tassigny, Xavier, Fee, John, Huntsman, David G, McKinney, Steven, Poon, Steven, Prentice, Leah M, Ruiz de Algara, Teresa, Sutcliffe, Margaret, Turashvili, Gulisa, Yap, Damian   +13 more
core   +2 more sources

Lemongrass (Cymbopogon citratus) Extracts Ameliorate Polycystic Ovary Syndrome in Rats by Inhibiting Follicular Atresia and Modulating Ghrelin and Leptin

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Polycystic ovary syndrome (PCOS) accelerates ovarian follicular depletion through atresia. This study investigated the therapeutic potential of aqueous (AE) and hydroethanolic (HEE) extracts of Cymbopogon citratus in mitigating PCOS‐induced ovarian damage (specifically ferroptosis, apoptosis, and oxidative stress) in a rat model of PCOS.
Vanis Slauvers Akago, Marie Alfrede Mvondo, Sefirin Djiogue, Stephen Lacmata Tamekou, Nina-Sonia Messongue Mbollo, Josue Jobin Biba, Agatha Yelah Ntumnyuy, Lylie Gisèle Atsafack Mboudem, Perpetue Atsama Mbede, Christophe Mezui, Hélène Carole Edima-Durand, Jules-Roger Kuiate, Dieudonné Njamen, Yoel Klug   +13 more
wiley   +1 more source

Correlation Between Serum Kisspeptin Levels and Pregnancy Outcomes in Frozen Embryo Transfer Cycles in Polycystic Ovary Syndrome Patients

Clinical and Experimental Obstetrics & Gynecology
Background: Kisspeptin, a key regulator of the hypothalamic-pituitary-ovarian (HPO) axis through GnRH stimulation, is implicated in polycystic ovary syndrome (PCOS) pathogenesis via HPO axis dysregulation.
Li Ling, Di Xia, Mengzhu Chen, Yuanjiao Liang, Xia Zhao   +4 more
doaj   +1 more source