Results 101 to 110 of about 16,602 (265)

Dynamic Kisspeptin Receptor Trafficking Modulates Kisspeptin-Mediated Calcium Signaling [PDF]

Molecular Endocrinology, 2014
AbstractKisspeptin receptor (KISS1R) signaling plays a critical role in the regulation of reproduction. We investigated the role of kisspeptin-stimulated KISS1R internalization, recycling, and degradation in the modulation of KISS1R signaling. Kisspeptin stimulation of Chinese hamster ovary or GT1–7 cells expressing KISS1R resulted in a biphasic ...
Rona S. Carroll, Ursula B. Kaiser, Wendy Kuohung, Ana Claudia S. Reis, Ana Claudia S. Reis, Le Min, Manisha Jain, Kathleen A. Soltis, Shuyun Xu   +8 more
openaire   +2 more sources

IMPROVE 2023: The 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence

Clinical Obesity, Volume 15, Issue 5, October 2025.
ABSTRACT A total of 150 clinicians and researchers representing 19 countries came together in person and online to participate in the highly anticipated 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE), held on 13–15 December 2023 in Paris, France.
Karine Clément, Erica L. T. van den Akker, Jesús Argente, Phil Beales, Metin Cetiner, Béatrice Dubern, Sadaf Farooqi, Aurélie Gouronc, Peter Kühnen, Johanne Le Beyec, Louis Lebreton, David Meeker, Hermann L. Müller, Jean Muller, Christine Poitou, Patrick Sleiman, Christian Vaisse, Martin Wabitsch, Jacques Young, Hélène Dollfus   +19 more
wiley   +1 more source

Correlation Between Serum Kisspeptin Levels and Pregnancy Outcomes in Frozen Embryo Transfer Cycles in Polycystic Ovary Syndrome Patients

Clinical and Experimental Obstetrics & Gynecology
Background: Kisspeptin, a key regulator of the hypothalamic-pituitary-ovarian (HPO) axis through GnRH stimulation, is implicated in polycystic ovary syndrome (PCOS) pathogenesis via HPO axis dysregulation.
Li Ling, Di Xia, Mengzhu Chen, Yuanjiao Liang, Xia Zhao   +4 more
doaj   +1 more source

Hormonal regulation of female reproduction [PDF]

, 2012
Reproduction is an event that requires the coordination of peripheral organs with the nervous system to ensure that the internal and external environments are optimal for successful procreation of the species.
Bentley, G. E., Cabrera Kreiker, Ricardo Jorge, Christensen, A., Micevych, P., Ortega, Hugo Hector, Perfito, N., Wu, T. J.   +6 more
core   +1 more source

Low Degree of Overlap Between Kisspeptin, Neurokinin B, and Dynorphin Immunoreactivities in the Infundibular Nucleus of Young Male Human Subjects Challenges the KNDy Neuron Concept. [PDF]

, 2012
Previous immunohistochemical and in situ hybridization studies of sheep, goats, and rodents indicated that kisspeptin (KP), neurokinin B (NKB), and dynorphin A (DYN) are extensively colocalized in the hypothalamic arcuate nucleus, thus providing a basis ...
Borsay, Beáta Ágnes, Ciofi, Philippe, Gergely, Péter, Herczeg, László, Hrabovszky, Erik, Liposits, Zsolt, Molnár, Csilla, Sipos, Máté   +7 more
core   +1 more source

Reproduction and beyond, kisspeptin in ruminants [PDF]

Journal of Animal Science and Biotechnology, 2015
Kisspeptin (Kp) is synthesized in the arcuate nucleus and preoptic area of the hypothalamus and is a regulator of gonadotropin releasing hormone in the hypothalamus. In addition, Kp may regulate additional functions such as increased neuropeptide Y gene expression and reduced proopiomelanocortin (POMC) gene expression in sheep. Other studies have found
Brian K Whitlock, Chad D. Foradori, Joseph A Daniel, James L. Sartin   +3 more
openaire   +3 more sources

Distinct patterns of hypogonadism in a cross‐sectional study of Malaysian men with type 2 diabetes mellitus: The role of insulin resistance, visceral adiposity, and aging

Journal of Diabetes Investigation, Volume 16, Issue 10, Page 1881-1889, October 2025.
Age is significantly associated with hypergonadotropic hypogonadism, while insulin resistance and visceral adiposity are strongly linked to hypogonadotropic hypogonadism. Older and obese Malaysian type 2 diabetes mellitus males, particularly those with coronary artery disease and lower HDL‐C levels, are at higher risk.
Waye‐Hann Kang, Norlela Sukor, Nor Azmi Kamaruddin   +2 more
wiley   +1 more source

KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion [PDF]

, 2011
KISS1 and its receptor, KISS1R, have both been found to be expressed in central nervous system, but few data are present in the literature about their distribution in peripheral nervous structures.
De Caro, Raffaele, Fenu, Grazia, Macchi, Veronica, Malendowicz, Ludwik K., Montella, Andrea Costantino Mario, Porzionato, Andrea, Ruciński, Marcin   +6 more
core  

Xenoestrogens Ethinyl Estradiol and Zearalenone Cause Precocious Puberty in Female Rats via Central Kisspeptin Signaling [PDF]

, 2015
Xenoestrogens from synthetic or natural origin represent an increasing risk of disrupted endocrine functions including the physiological activity of the hypothalamo-pituitary-gonad axis.
Csilla Molnár, Dániel Kuti, Erik Hrabovszky, Imre Kalló, Krisztina J. Kovács, Rókus Kriszt, Szilamér Ferenczi, Zsuzsanna Szőke, Zsuzsanna Winkler, Ágnes Polyák   +9 more
core   +1 more source

The Role of Kisspeptin in Sexual Behavior [PDF]

Seminars in Reproductive Medicine, 2019
AbstractSexual behavior is essential for the perpetuation of a species. In female rodents, mate preference and lordosis behavior depend heavily on the integration of olfactory cues into the neuroendocrine brain, yet its underlying neural circuits are not well understood.
Hellier, Vincent, Brock, Olivier, Bakker, Julie   +2 more
openaire   +4 more sources