Results 111 to 120 of about 16,997 (262)
The Role of Neurotransmitters in Protection against Amyloid- β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons. [PDF]
, 2013 Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide.
Chilumuri, A. +3 more
core +6 more sources
Central precocious puberty: From genetics to treatment [PDF]
, 2018 Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A. +1 more
core +1 more source
eLife, 2019 The brain regulates fertility through gonadotropin-releasing hormone (GnRH) neurons. Estradiol induces negative feedback on pulsatile GnRH/luteinizing hormone (LH) release and positive feedback generating preovulatory GnRH/LH surges.
Luhong Wang +6 more
doaj +1 more source
Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice. [PDF]
, 2019 BackgroundThe mechanisms whereby neuroinflammation negatively affects neuronal function in the hypothalamus are not clear. Our previous study determined that obesity-mediated chronic inflammation elicits sex-specific impairment in reproductive function ...
Coss, Djurdjica, Lainez, Nancy M
core +1 more source
Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain [PDF]
, 2018 The mammalian brain undergoes sexual differentiation by gonadal hormones during the perinatal critical period. However, the machinery at earlier stages has not been well studied.
Fujiyama Tomoyuki +20 more
core +2 more sources
Effect of apple vinegar on folliculogenesis and ovarian kisspeptin in a high-fat diet-induced nonalcoholic fatty liver disease in rat [PDF]
, 2022 Fahimeh Shams +4 more
openalex +1 more source
A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10
American Journal of Physiology-Endocrinology and Metabolism, 2010 The kisspeptins are neuropeptides that stimulate the hypothalamo-pituitary-gonadal (HPG) axis. The smallest endogenous kisspeptin, kisspeptin-10 (KP-10), binds to the receptor KISS1R with a similar affinity to the full-length peptide, kisspeptin-54 (KP-54), but is less effective in vivo, possibly because of increased enzymatic breakdown or clearance ...
Curtis, Annette E. +7 more
openaire +3 more sources
Potential role of Kisspeptin in infertility [PDF]
BIO Web of ConferencesKisspeptin is a neuropeptide that plays a central role in fertility and neuroendocrine regulation of the hypothalamic-pituitary-gonadal axis. It has also been shown to act at the peripheral level in both men and women.
Konaté Oumar +5 more
doaj +1 more source