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Kisspeptin and Glucose Homeostasis

Seminars in Reproductive Medicine, 2019
AbstractKisspeptin has well-established critical roles in the control of reproduction and fertility. Recently, evidence has emerged that suggests kisspeptin may have additional roles in the regulation of glucose homeostasis. Conflicting reports on the effects of kisspeptin on insulin secretion in animal models have been published, which cannot be fully
Izzi-Engbeaya, Chioma   +2 more
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Kisspeptin and Seasonality of Reproduction

2013
Wild and domesticated species display seasonality in reproductive function, controlled predominantly by photoperiod. Seasonal alterations in breeding status are caused by changes in the secretion of gonadotropin-releasing hormone (GnRH) that are mediated by upstream neuronal afferents that regulate the GnRH cells.
Clarke, Iain J, Caraty, Alain
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Kisspeptin as a Behavioral Hormone

Seminars in Reproductive Medicine, 2019
AbstractSuccessful reproduction is dependent not only on hormonal endocrine responses but also on suitable partner selection, copulatory acts, as well as associated emotional, behavioral, and cognitive processes many of which are supported by the limbic system.
Mills, EGA, O'Byrne, KT, Comninos, AN
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Kisspeptin and Gynecological Cancer

Proceedings of the Fourth International Conference on Biological Information and Biomedical Engineering, 2020
Background: Kisspeptin was identified in 1996 and it was known as a suppressor of metastatic malignant tumors. Kisspeptin and its receptor KISS1R have been identified as potential prognostic or therapeutic markers in cancers. Recent study suggested that kisspeptin plays an important role in gynecological cancer, including breast cancer, ovarian cancer,
openaire   +1 more source

GPR54 and Kisspeptins

2008
The G-protein coupled receptor GPR54 has an essential role in the initiation and maintenance of mammalian fertility. Humans and mice with mutations in GPR54 have hypogonadotropic hypogonadism characterized by absence of sexual maturation and low levels of gonadotropic hormones (LH and FSH).
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Kisspeptins, Estrogens and Male Fertility

Current Medicinal Chemistry, 2016
The control of male fertility requires accurate endocrine, paracrine and autocrine communications along the hypothalamus-pituitary-gonad (HPG) axis. In this respect, the possible interplay between upcoming/classical modulators of reproductive functions deserves attention in that may be a successful tool for the future exploitation of new potential ...
CHIANESE, Rosanna   +7 more
openaire   +3 more sources

Metabolic Regulation of Kisspeptin

2013
Body energy balance and metabolic signals are important modulators of puberty and reproductive function, so that perturbations of metabolism and energy reserves (ranging from persistent energy insufficiency to morbid obesity) are frequently linked to reproductive disorders.
Juan Manuel, Castellano   +1 more
openaire   +2 more sources

Expression of kisspeptins and kisspeptin receptor in the kidney of chronic renal failure rats

Peptides, 2010
Kisspeptins are biologically active cleavage peptides of the KiSS-1 gene products with important roles in the suppression of tumor metastasis and in the reproduction. The aim of the present study is to clarify changes of the expression of kisspeptins and kisspeptin receptor in the kidney with and without chronic renal impairment.
Itaru, Shoji   +13 more
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Kisspeptins and kisspeptin receptors in the rat and human carotid body

Italian Journal of Anatomy and Embryology, 2010
Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement ...
Porzionato, Andrea   +6 more
openaire   +1 more source

Electrophysiology of Kisspeptin Neurons

2013
Kisspeptin is an important regulator of reproduction. Electrophysiological studies show that kisspeptin neurons of the arcuate nucleus that co-localize neurokinin B and dynorphin (aka KNDy neurons) fire action potentials in a tonic, irregular, or burst firing manner. Gonadectomy dramatically alters the membrane properties of KNDY neurons from male mice
openaire   +2 more sources

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