Results 121 to 130 of about 21,456 (303)

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

Experimental Physiology, EarlyView.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller, M. Erin Moir, Brandon G. Fico   +2 more
wiley   +1 more source

Hypothalamic kisspeptin and kisspeptin receptors: Species variation in reproduction and reproductive behaviours

Frontiers in Neuroendocrinology, 2022
Kisspeptin, encoded by the KISS1 gene, was first discovered as a potential metastasis suppressor gene. The prepro-kisspeptin precursor is cleaved into shorter mature bioactive peptides of varying sizes that bind to the G protein-coupled receptor GPR54 (=KISS1R).
Mageswary Sivalingam, Ishwar S. Parhar
openaire   +2 more sources

Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat. [PDF]

PLoS ONE, 2009
BACKGROUND:Kisspeptin and its G protein-coupled receptor (GPR) 54 are essential for activation of the hypothalamo-pituitary-gonadal axis. In the rat, the kisspeptin neurons critical for gonadotropin secretion are located in the hypothalamic arcuate (ARC)
Xiao-Feng Li, James S Kinsey-Jones, Yewsong Cheng, Alice M I Knox, Yuanshao Lin, Nikoletta A Petrou, Antonia Roseweir, Stafford L Lightman, Stuart R Milligan, Robert P Millar, Kevin T O'Byrne   +10 more
doaj   +1 more source

Follicle size on day of trigger most likely to yield a mature oocyte [PDF]

, 2018
Funding: MRC, BBSRC and NIHR and supported by the NIHR/Wellcome Trust Imperial Clinical Research Facility and Imperial Biomedical Research Centre.Objective: To identify follicle sizes on the day of trigger most likely to yield a mature oocyte following ...
Alexander N. Comninos, Ali Abbara, Geoffrey H. Trew, Lan N. Vuong, Lan N. Vuong, Lisa Jeffers, Peter Humaidan, Rehan Salim, Sophie A. Clarke, Tom W. Kelsey, Tuong M. Ho, Vu N. A. Ho, Waljit S. Dhillo   +12 more
core   +3 more sources

Kisspeptin-10 Rescues Cholinergic Differentiated SHSY-5Y Cells from α-Synuclein-Induced Toxicity In Vitro [PDF]

, 2022
Christopher A. Simon, Tomoko Soga, Nafees Ahemad, Saatheeyavaane Bhuvanendran, Ishwar S. Parhar   +4 more
openalex   +1 more source

Progesterone receptors in AVPV kisspeptin neurons are sufficient for positive feedback induction of the LH surge.

Endocrinology, 2021
Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In female rodents, estrogen-sensitive kisspeptin neurons in the rostral anteroventral periventricular (AVPV) hypothalamus are thought to mediate estradiol (E2)-induced positive
M. Mohr, L. Esparza, Paige Steffen, P. Micevych, A. Kauffman   +4 more
semanticscholar   +1 more source

Neuroanatomical evidence that kisspeptin directly regulates isotocin and vasotocin neurons. [PDF]

PLoS ONE, 2013
Neuropeptide kisspeptin has been suggested to be an essential central regulator of reproduction in response to changes in serum gonadal steroid concentrations.
Shinji Kanda, Yasuhisa Akazome, Yuta Mitani, Kataaki Okubo, Yoshitaka Oka   +4 more
doaj   +1 more source

Correlation Between Serum Kisspeptin Levels and Pregnancy Outcomes in Frozen Embryo Transfer Cycles in Polycystic Ovary Syndrome Patients

Clinical and Experimental Obstetrics & Gynecology
Background: Kisspeptin, a key regulator of the hypothalamic-pituitary-ovarian (HPO) axis through GnRH stimulation, is implicated in polycystic ovary syndrome (PCOS) pathogenesis via HPO axis dysregulation.
Li Ling, Di Xia, Mengzhu Chen, Yuanjiao Liang, Xia Zhao   +4 more
doaj   +1 more source

A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]

, 2016
Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
core   +1 more source

Hormonal regulation of female reproduction [PDF]

, 2012
Reproduction is an event that requires the coordination of peripheral organs with the nervous system to ensure that the internal and external environments are optimal for successful procreation of the species.
Bentley, G. E., Cabrera Kreiker, Ricardo Jorge, Christensen, A., Micevych, P., Ortega, Hugo Hector, Perfito, N., Wu, T. J.   +6 more
core   +1 more source