Results 121 to 130 of about 16,602 (265)
The Roles of the Amygdala Kisspeptin System
Seminars in Reproductive Medicine, 2019 AbstractThe hypothalamic hormone kisspeptin (encoded by the KISS1/kiss1 gene) is the master regulator of the reproductive axis with its role in controlling gonadotrophin hormone secretion now well characterized. However, identification of kisspeptin and its cognate receptor expression within the amygdala, a key limbic brain region whose functions ...
Alexander N Comninos +3 more
openaire +4 more sources
Central precocious puberty: From genetics to treatment [PDF]
, 2018 Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A. +1 more
core +1 more source
The Role of Kisspeptin in Female Reproduction
International Journal of Endocrinology and Metabolism, 2017 Kisspeptin (KISS1), a recently discovered neuropeptide that acts upstream of gonadotropin-releasing hormone (GnRH) neurons, is critical for maturation and function of the reproductive axis. This review aimed at providing comprehensive and up-to-date information on Kisspeptin and its role in female reproduction.A literature review was performed using ...
Sareh Zeydabadi Nejad +2 more
openaire +3 more sources
Understanding women's sex hormone physiology—A priority in diabetes care
Diabetic Medicine, Volume 42, Issue 10, October 2025.
Céline Isabelle Laesser +4 more
wiley +1 more source
Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice. [PDF]
, 2019 BackgroundThe mechanisms whereby neuroinflammation negatively affects neuronal function in the hypothalamus are not clear. Our previous study determined that obesity-mediated chronic inflammation elicits sex-specific impairment in reproductive function ...
Coss, Djurdjica, Lainez, Nancy M
core +1 more source
A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10
American Journal of Physiology-Endocrinology and Metabolism, 2010 The kisspeptins are neuropeptides that stimulate the hypothalamo-pituitary-gonadal (HPG) axis. The smallest endogenous kisspeptin, kisspeptin-10 (KP-10), binds to the receptor KISS1R with a similar affinity to the full-length peptide, kisspeptin-54 (KP-54), but is less effective in vivo, possibly because of increased enzymatic breakdown or clearance ...
Stephen R. Bloom +7 more
openaire +4 more sources
The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54 [PDF]
, 2001 Masato Kotani +13 more
openalex +1 more source
Kisspeptin: A Central Regulator of Reproduction in Mammals
SVU-International Journal of Veterinary Sciences, 2019 The discovery of the role of kisspeptin neurons in the regulation of mammalian reproduction in 2003 was one of the biggest breakthroughs in reproductive endocrinology within the last few decades.
Nahoko Ieda +4 more
doaj +1 more source
Central and Peripheral Administration of Kisspeptin‐10 Stimulates the Hypothalamic‐Pituitary‐Gonadal Axis [PDF]
, 2004 Emily L. Thompson +7 more
openalex +1 more source
Poultry ScienceKisspeptin, acting as both a neuropeptide and a hormone, known for its pivotal role in reproductive function and energy homeostasis, exerts multifaceted effects on central nervous system pathways involved in appetite regulation.
Hamed Zarei +4 more
doaj +1 more source