Results 141 to 150 of about 21,456 (303)
KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion [PDF]
, 2011 KISS1 and its receptor, KISS1R, have both been found to be expressed in central nervous system, but few data are present in the literature about their distribution in peripheral nervous structures.
De Caro, Raffaele +6 more
core
RF01 | PMON44 Absence of Kisspeptin in KNDy Neurons of Mice Causes Sexually Dimorphic Metabolic Dysfunction on a High-Fat Diet [PDF]
, 2022 Nimisha Nandankar +4 more
openalex +1 more source
Pharmacokinetics and Safety of Fezolinetant in Women with Hepatic or Renal Impairment
The Journal of Clinical Pharmacology, Volume 65, Issue 11, Page 1517-1530, November 2025.Abstract The neurokinin 3 receptor antagonist fezolinetant is an approved treatment for vasomotor symptoms due to menopause. The impacts of hepatic and renal impairment on the pharmacokinetics and safety of a single oral dose of fezolinetant 30 mg were investigated in two independent studies.
Megumi Iwai +8 more
wiley +1 more source
Andrology, Volume 13, Issue 8, Page 2022-2034, November 2025.Abstract Background Hypogonadism and infertility are two conditions that are heavily affected by overweight and obesity in the male patient. Glucagon‐like peptide 1 agonists (GLP‐1RAs) are a recently introduced class of antidiabetic drugs with powerful weight‐loss effect; this may induce an indirect positive effect on the testicular function ...
Gianmaria Salvio +6 more
wiley +1 more source
Stress rapidly suppresses in vivo LH pulses and increases activation of RFRP-3 neurons in male mice [PDF]
, 2018 Restraint stress is a psychosocial stressor that suppresses reproductive status, including LH pulsatile secretion, but the neuroendocrine mechanisms underlying this inhibition remains unclear.
Hughes, Jessica K +4 more
core +1 more source
Journal of Neuroendocrinology, Volume 37, Issue 11, November 2025.Abstract The mouse brain is masculinized by postnatal testicular androgens, which are active after conversion to estrogens and modulate gene expression epigenetically, at least in part. The preoptic area contains a sexually dimorphic nucleus (SDN) comprising calbindin D‐28K (Calb) neurons with a male‐biased sex difference in cell number (Calb‐SDN ...
Yusa Arai, Shinji Tsukahara
wiley +1 more source
The Roles of the Amygdala Kisspeptin System
Seminars in Reproductive Medicine, 2019 AbstractThe hypothalamic hormone kisspeptin (encoded by the KISS1/kiss1 gene) is the master regulator of the reproductive axis with its role in controlling gonadotrophin hormone secretion now well characterized. However, identification of kisspeptin and its cognate receptor expression within the amygdala, a key limbic brain region whose functions ...
Mills, EGA, O'Byrne, KT, Comninos, AN
openaire +4 more sources
The Role of Neurotransmitters in Protection against Amyloid- β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons. [PDF]
, 2013 Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide.
Chilumuri, A. +3 more
core +6 more sources
Kisspeptin and Endometriosis—Is There a Link?
Journal of Clinical MedicineThis article presents a narrative review that explores the potential link between kisspeptin—a key regulator of the hypothalamic-pituitary-gonadal axis—and the pathogenesis of endometriosis. Kisspeptin plays a significant role in regulating reproductive functions by modulating the release of gonadotropin-releasing hormone (GnRH), which in turn ...
Blazej Meczekalski +5 more
openaire +2 more sources
Design and synthesis of fluorescent probes for GPR54. [PDF]
, 2014 Kisspeptins are neuropeptides that induce the secretion of gonadotropin-releasing hormone via the activation of the cognate receptor, G-protein coupled receptor 54 (GPR54).
Fujii, Nobutaka +9 more
core +1 more source