Results 151 to 160 of about 21,456 (303)

Central precocious puberty: From genetics to treatment [PDF]

open access: yes, 2018
Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A.   +1 more
core   +1 more source

Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction

open access: yeseLife, 2019
The brain regulates fertility through gonadotropin-releasing hormone (GnRH) neurons. Estradiol induces negative feedback on pulsatile GnRH/luteinizing hormone (LH) release and positive feedback generating preovulatory GnRH/LH surges.
Luhong Wang   +6 more
doaj   +1 more source

Central Mechanism Controlling Pubertal Onset in Mammals: A Triggering Role of Kisspeptin [PDF]

open access: gold, 2019
Yoshihisa Uenoyama   +3 more
openalex   +1 more source

A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 2010
The kisspeptins are neuropeptides that stimulate the hypothalamo-pituitary-gonadal (HPG) axis. The smallest endogenous kisspeptin, kisspeptin-10 (KP-10), binds to the receptor KISS1R with a similar affinity to the full-length peptide, kisspeptin-54 (KP-54), but is less effective in vivo, possibly because of increased enzymatic breakdown or clearance ...
Curtis, Annette E.   +7 more
openaire   +3 more sources

Potential role of Kisspeptin in infertility [PDF]

open access: yesBIO Web of Conferences
Kisspeptin is a neuropeptide that plays a central role in fertility and neuroendocrine regulation of the hypothalamic-pituitary-gonadal axis. It has also been shown to act at the peripheral level in both men and women.
Konaté Oumar   +5 more
doaj   +1 more source

Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice. [PDF]

open access: yes, 2019
BackgroundThe mechanisms whereby neuroinflammation negatively affects neuronal function in the hypothalamus are not clear. Our previous study determined that obesity-mediated chronic inflammation elicits sex-specific impairment in reproductive function ...
Coss, Djurdjica, Lainez, Nancy M
core   +1 more source

Kisspeptins and the neuroendocrine control of reproduction: Recent progress and new frontiers in kisspeptin research

open access: yesFrontiers in neuroendocrinology (Print), 2022
V. Sobrino   +4 more
semanticscholar   +1 more source

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