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Hypervirulent Klebsiella pneumoniae [PDF]

open access: yesClinical Microbiology Reviews, 2019
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are often healthy.
Thomas A, Russo, Candace M, Marr
openaire   +3 more sources

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

open access: yesNature Communications, 2021
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-associated infections, neonatal sepsis and community-acquired liver abscess, and is associated with chronic intestinal diseases.
M. Lam   +5 more
semanticscholar   +1 more source

Characteristics of antibiotic resistance mechanisms and genes of Klebsiella pneumoniae

open access: yesOpen Medicine, 2023
Klebsiella pneumoniae is an important multidrug-resistant (MDR) pathogen that can cause a range of infections in hospitalized patients. With the growing use of antibiotics, MDR K. pneumoniae is more prevalent, posing additional difficulties and obstacles
Yanping Li   +4 more
semanticscholar   +1 more source

Regulation of biofilm formation in Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2023
Klebsiella pneumoniae is an important Gram-negative opportunistic pathogen that is responsible for a variety of nosocomial and community-acquired infections. Klebsiella pneumoniae has become a major public health issue owing to the rapid global spread of
Yin Li, Ming Ni
semanticscholar   +1 more source

Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
The ability to form biofilms is a crucial virulence trait for several microorganisms, including Klebsiella pneumoniae – a Gram-negative encapsulated bacterium often associated with nosocomial infections.
M. E. Guerra   +7 more
semanticscholar   +1 more source

Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae

open access: yesNature Communications, 2022
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ceftazidime ...
Anaïs Eskenazi   +17 more
semanticscholar   +1 more source

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

open access: yesJournal of Internal Medicine, 2020
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing community‐acquired infections, often in healthy individuals.
Jacob E. Choby   +2 more
semanticscholar   +1 more source

The Characteristic of Virulence, Biofilm and Antibiotic Resistance of Klebsiella pneumoniae

open access: yesInternational Journal of Environmental Research and Public Health, 2020
Klebsiella pneumoniae is an important gram-negative opportunistic pathogen that causes a variety of infectious diseases, including urinary tract infections, bacteremia, pneumonia, and liver abscesses.
Guoying Wang   +4 more
semanticscholar   +1 more source

Virulence Factors in Hypervirulent Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2021
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the Asian Pacific Rim. It is an invasive variant that differs from the classical K.
Jie Zhu, Tao Wang, Liang Chen, Hong Du
semanticscholar   +1 more source

Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China

open access: yesEmerging Microbes and Infections, 2022
The epidemiological features of the newly emerged carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) and its potential threat to human health are currently unknown.
Xuemei Yang   +9 more
semanticscholar   +1 more source

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