High yield 1,3-propanediol production by rational engineering of the 3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii [PDF]
Background: Imbalance in cofactors causing the accumulation of intermediates in biosynthesis pathways is a frequently occurring problem in metabolic engineering when optimizing a production pathway in a microorganism.
Avcı, Fatma Gizem+5 more
core +3 more sources
A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan+12 more
wiley +1 more source
Prevalence and antimicrobial resistance of Enterobacteriaceae in the north of Kazakhstan
Background: An increasing number of drugs are used each year in the treatment of small pets (cats and dogs), including medicines (cephalosporins and fluoroquinolones) used in human therapy. Aim: The purpose of this study was to isolate and explore the
Yuliya Aleshina+4 more
doaj +1 more source
Stem Rot of Pearl Millet Prevalence, Symptomatology, Disease Cycle, Disease Rating Scale and Pathogen Characterization in Pearl Millet-Klebsiella Pathosystem [PDF]
The oldest and most extensively cultivated form of millet, known as pearl millet (Pennisetum glaucum (L.) R. Br. Syn. Pennisetum americanum (L.) Leeke), is raised over 312.00 lakh hectares in Asian and African countries.
Vinod Kumar Malik+13 more
doaj +1 more source
A surge of extended spectrum beta lactamase (ESBL)-producers is being witnessed in the neonatal intensive care units (NICUs). Hence, the present study was conducted to analyze both the bacteriological profile and clinical outcome of neonatal septicemia ...
Dina M. Hassan+2 more
doaj +1 more source
Social geography of rhinoscleroma and qualitatively and quantitatively abnormal cell-mediated immunity [PDF]
Rhinoscleroma is a progressive chronic granulomatous disease of the upper respiratory tract that may extend to the tracheobronchial tract. It is common belief that the pathology is determined by Klebsiella Rhinoscleromatis.
A. Ciofalo+5 more
core +1 more source
Adapting Image‐Based Models for 1D Data via Spider Plot Transformation and Transfer Learning
A novel method enables the use of pretrained image‐based neural networks for complex 1D data, including Raman and mid‐infrared spectra, electrocardiograms, and mass spectrometry. 2D spider plots with false‐color fill enable transfer lerning, therefore enhancing data augmentation and model explainability across diverse spectral and time series datasets.
Azadeh Mokari+2 more
wiley +1 more source
Global burden of colistin-resistant bacteria : mobilized colistin resistance genes study (1980-2018) [PDF]
Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The recent global dissemination of mobilized colistin resistance (mcr) genes is an urgent public health threat.
Elbediwi, Mohammed+10 more
core +1 more source
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero+17 more
wiley +1 more source
Antibiotic prophylaxis is associated with subsequent resistant infections in children with an initial extended-spectrum-cephalosporin-resistant Enterobacteriaceae infection [PDF]
The objective of this study was to assess the association between previous antibiotic use, particularly long-term prophylaxis, and the occurrence of subsequent resistant infections in children with index infections due to extended-spectrum-cephalosporin ...
Adler, Amanda L+12 more
core +2 more sources