Results 131 to 140 of about 12,659 (217)
Delineation of Klf2 domains required for reprogramming EpiSCs to iPSCs.
(A) Western blot analysis of EpiSCs expressing epitope-tagged Klf2 and deletion (Δ) mutants. Closed arrowheads indicate epitope-tagged Klf2 proteins. (B) Fluorescence images of a reprogrammed Oct3/4-ΔPE-GFP EpiSC colony with a Klf2 deletion domain on day
Jun Yanagisawa (2550943) +6 more
core +1 more source
Foam cell formation, a hallmark of early atherosclerotic lesion development, is closely associated with mitochondrial dysfunction and excessive reactive oxygen species (ROS) production.
Md Sariful Islam Howlader +4 more
doaj +1 more source
KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1
Summary: Human spermatogonial stem cells (SSCs) are essential for spermatogenesis and male fertility. However, molecular mechanisms regulating fate determinations of human SSCs remain elusive.
Wei Chen +6 more
doaj +1 more source
Background Chronic kidney disease causes endothelial cell dysfunction associated with uremia, which triggers a high risk of cardiovascular diseases. Furthermore, prolonged exposure of the vascular endothelium to uremic toxins could provoke endothelial ...
Danjun Wang +3 more
doaj +1 more source
Flow hemodynamics regulates endothelial cell (EC) responses and laminar shear stress induces an atheroprotective and quiescent phenotype. The flow-responsive transcription factor KLF2 is a pivotal mediator of endothelial quiescence, but the precise ...
Doddaballapur, Anuradha
core
KLF2 Upregulates miR-483 to Modulate Endothelial Function [PDF]
.KLF2, originally named lung kruppel-like factor (LKLF), is a zinc finger transcription factor that is heavily involved in vascular development. Recent studies have identified this shear stress responsive gene as a key regulator of endothelial function ...
Woo, Brian Justin
core
KLF2 determines the susceptibility of T cells to immunoregulatory NK cells.
Abstract Natural killer (NK) cells suppress cellular and humoral immune responses via killing of T cells, resulting in diminished vaccine responses in mice and humans. Efforts to overcome this roadblock and achieve optimal immunity require an improved understanding of the molecular mediators facilitating NK cell-targeting of discrete subsets of
Stephen Waggoner +8 more
openaire +2 more sources

