Results 261 to 270 of about 18,442 (279)

supplement_table-KLF2 – Supplemental material for KLF2 Inhibits the Migration and Invasion of Prostate Cancer Cells by Downregulating MMP2

2018
Supplemental material, supplement_table-KLF2 for KLF2 Inhibits the Migration and Invasion of Prostate Cancer Cells by Downregulating MMP2 by Binshuai Wang, Mingyuan Liu, Yimeng Song, Changying Li, Shudong Zhang and Lulin Ma in American Journal of Men’s ...
Binshuai Wang, Mingyuan Liu, Yimeng Song, Changying Li, Shudong Zhang, Lulin Ma   +5 more
openaire   +1 more source

KLF2 enhancer variant rs4808485 increases lupus risk by modulating inflammasome machinery and cellular homoeostasis

Annals of the Rheumatic Diseases
Objective A recent genome-wide association study linked KLF2 as a novel Asian-specific locus for systemic lupus erythematosus (SLE) susceptibility.
M. K. Singh, H. Rallabandi, Xu-jie Zhou, Y. Qi, Zhan-zheng Zhao, Ting Gan, Hong Zhang, Loren L. Looger, S. Nath   +8 more
semanticscholar   +1 more source

KLF2 Inhibits Ferroptosis and Improves Mitochondrial Dysfunction in Chondrocyte Through SIRT1/GPX4 Signaling to Improve Osteoarthritis

Drug development research (Print)
Osteoarthritis (OA), a disease of articular joints, is the leading cause of disability in the elderly. Repressing ferroptosis and improving mitochondrial function can delay the progression of OA. Kruppel‐like factor 2 (KLF2) exerts a protective effect on
Jiaqi Shi, Li Chen, Xu Wang, Xin Ma
semanticscholar   +1 more source

Med1 controls thymic T‐cell migration into lymph node through enhancer‐based Foxo1‐Klf2 transcription program

European Journal of Immunology
The migration is the key step for thymic T cells to enter circulation and then lymph nodes (LNs), essential for future immune surveillance. Although promoter‐based transcriptional regulation through Foxo1, Klf2, Ccr7, and Sell regulates T‐cell migration,
Ning Yuan, Yanhong Su, Yang Gao, Biao Yang, Tianzhe Zhang, Qianhao Wang, Dan Zhang, Lin Shi, Anjun Jiao, Lei Lei, Lina Sun, Baojun Zhang   +11 more
semanticscholar   +1 more source

Netrin‐1 protects blood–brain barrier (BBB) integrity after cerebral ischemia‐reperfusion by activating the Kruppel‐like factor 2 (KLF2)/occludin pathway

Journal of biochemical and molecular toxicology
Ischemia/reperfusion (I/R)‐induced neural damage and neuroinflammation have been associated with pathological progression during stroke. Netrin‐1 is an important member of the family of laminin‐related secreted proteins, which plays an important role in ...
Yuanxiao Li, Changyun Liu, Zhiting Chen, Hanbin Lin, Xiaofeng Li   +4 more
semanticscholar   +1 more source

KLF2-dependent transcriptional regulation safeguards the heart against pathological hypertrophy

Journal of Molecular and Cellular Cardiology
Our previous single-cell RNA sequencing study in the adult human heart revealed that cardiomyocytes from both the atrium and ventricle display high activities of Krüppel-like factor 2 (KLF2) regulons. However, the role of the transcription factor KLF2 in cardiomyocyte biology remains largely unexplored.We employed transverse aortic constriction surgery
Yongqi, Wu, Yujuan, Song, Nan, Xie, Wanqing, Zhao, Jian, Lv, Tingting, Zhang, Yang, Zhang, Hongyin, Chen, Weiyun, Sun, Zhenyu, Luo, Xinhui, Cheng, Tao, Jiang, Zhihua, Wang, Xiaoling, Chen, Yu, Hu, Yu, Fang, Rui, Bai, Xujie, Liu, Xia, He, Zongna, Ren, Juan, Huang, Hui, Xiong, Li, Wang   +22 more
openaire   +2 more sources

FOXP1 and KLF2 reciprocally regulate checkpoints of stem-like to effector transition in CAR T cells

Nature Immunology, 2023
Ziang Zhu, Guohua Lou, Xiao-Lu Teng, Haixia Wang, Ying Luo, Wangke Shi, Kiddist Yihunie, Shumeng Hao, Kole R. DeGolier, Chengheng Liao, Huocong Huang, Qing Zhang, Terry J. Fry, Tao Wang, Chen Yao, Tuoqi Wu   +15 more
semanticscholar   +1 more source

KLF2 IS REQUIRED FOR NORMAL MOUSE CARDIOVASCULAR DEVELOPMENT

2013
VCU Theses and ...
openaire   +1 more source

Lymph nodes fuel KLF2-dependent effector CD8+ T cell differentiation during chronic infection and checkpoint blockade

Nature Immunology
Carlson Tsui, Leonie Heyden, Lifen Wen, Catarina Gago da Graça, Nikita Potemkin, A. Frolov, Daniel Rawlinson, Lei Qin, Verena C. Wimmer, Marjan Hadian-Jazi, Darya Malko, Chun-Hsi Su, Sining Li, Kayla R. Wilson, Helena Horvatic, Sharanya K M Wijesinghe, Marcela L. Moreira, Lachlan Dryburgh, Dominik Schienstock, Lisa Rausch, Daniel T. Utzschneider, Cornelia Halin, Scott N. Mueller, M. Beyer, S. Bedoui, Zeinab Abdullah, Jan Schröder, Axel Kallies   +27 more
semanticscholar   +1 more source

MEF2C mitigates coronary artery lesions in Kawasaki disease by enhancing endothelial barrier function through KLF2 regulation.

International Immunopharmacology
Zhiwei Chen, Xinyu Di, Heyan Chen, Shengnan Song, Ruijie Chen, Longfa Kou, Maoping Chu   +6 more
semanticscholar   +1 more source