Results 121 to 130 of about 13,098 (199)

KMT2C and KMT2D amplify GRHL2-driven enhancer activation

Abstract The activation of cis-regulatory enhancers is essential for cell fate specification by driving cell type-specific gene expression. Differentiation models are widely used to study enhancer biology but the asynchronous and interdependent nature of gene regulatory changes during cell state transitions can complicate mechanistic ...
Ryan M. Boileau, Kevin X. Chen, Robert Blelloch   +2 more
openaire   +2 more sources

KMT2D wt Allele [PDF]

, 2020
openaire   +1 more source

KMT2D Gene Mutation [PDF]

, 2020
openaire   +1 more source

KMT2D depletion promotes KRAS-induced pancreatic carcinogenesis independent of TP53. [PDF]

J Biol Chem
Tolosa EJ, Raja Arul GL, Sigafoos AN, Ferrero V, Pease DR, Almada LL, Vera RE, Pena Ruiz NM, Hogenson TL, LaRue-Nolan KC, Tader BR, Graham RP, Brown M, Hagen CE, Matveyenko AV, Carr RM, Ge K, Fernandez-Zapico ME.   +17 more
europepmc   +1 more source

A Case of Nonimmune Hydrops Fetalis With a Duct-Dependent Systemic Circulation and a Novel Mutation of Kabuki Syndrome. [PDF]

Case Rep Genet
Prasad R, Sahoo S, Dalai R, Pathak KK, Chowdhary BK.   +4 more
europepmc   +1 more source

The Histone Methyltransferase KMT2D Is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration-Resistant Prostate Cancer. [PDF]

Cancer Res
Kittane S, Ladewig E, Li T, Love JR, Blawski R, Gao Y, Arruabarrena-Aristorena A, Zhao P, Dalrymple SL, Liu H, Guo X, Sallaku M, Kelkar N, Garcia-Martinez L, Carmona Sanz J, Chen W, Stoudmann C, Baldino L, Razavi-Mohseni M, Kalemi I, Beer MA, Castel P, Brennen WN, Scaltriti M, Morey L, Cocco E, Ji H, Chan HM, Battle A, Leslie CS, Karthaus WR, Toska E.   +31 more
europepmc   +1 more source

Next generation sequencing identifies novel gene alterations with potential prognostic relevance in pediatric cancer: a single-center study. [PDF]

Oncologist
Ma Y, Su M, Liu X, Wang W, Wu Y, Wang Z, Peng X, Xiong X, Lei J, Li Y.   +9 more
europepmc   +1 more source

A diagnostic pitfall in cold agglutinin disease: KMT2D-mutated CAD-associated lymphoproliferative disorder with a CLL-like immunophenotype. [PDF]

Oxf Med Case Reports
Okamoto Y, Arima H, Ishiyama K, Chonabayashi K, Kanda J, Yamashita K, Fujimoto M, Haga H, Nannya Y, Ogawa S, Takaori-Kondo A.   +10 more
europepmc   +1 more source

The Histone-Lysine N-Methyltransferase (KMT2) Family in Health and Disease. [PDF]

MedComm (2020)
Wang Q, Bo Z, Zhang Y, Chen Y, Wang Z, Tong S, Xu A, Zhang J, Liu Y.   +8 more
europepmc   +1 more source

Expanding the Anatomical Distribution of PRRX1::KMT2D Fusion Mesenchymal Neoplasms: A Rare Mediastinal Case Report. [PDF]

Cancer Rep (Hoboken)
Zhong W, Deng Y, Sun K.
europepmc   +1 more source