Results 121 to 130 of about 246,658 (352)

Distal femoral morphology as a risk factor for osteoarthritis

The Anatomical Record, EarlyView.
Abstract Osteoarthritis (OA) is a leading cause of disability affecting millions of adults in the United States, commonly resulting in the need for total knee arthroplasty (TKA) to restore mobility and quality of life. This study investigates potential differences in baseline distal femoral shape between individuals who received TKA due to OA and a ...
Haley Horbaly
wiley   +1 more source

Exploring the causal link among statin drugs and the osteoarthritis risk based on Mendelian randomization research

Frontiers in Genetics
PurposeStatins may have a protective effect against osteoarthritis (including knee osteoarthritis and hip osteoarthritis); however, the link between statins and osteoarthritis risk is incompletely established.
Wenjie Chen, Zhi Sun, Xinhai Xiong, Haitao Tan, Junhao Hu, Chenrui Liu, Cheng Chen   +6 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Associations Between Changes in Pain Sensitization and Disease Activity Following Disease‐Modifying Antirheumatic Drug Therapy in Established Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Abnormalities in pain regulatory mechanisms are common in patients with rheumatoid arthritis (RA). We investigated whether pain sensitization changes after treatment with a disease‐modifying antirheumatic drug (DMARD) and explored associations between changes in pain sensitization and disease activity.
Burcu Aydemir, Andrew C. Heisler, Lutfiyya N. Muhammad, Jing Song, Alyssa Wohlfahrt, Daniel J. Clauw, Wendy Marder, Marcy B. Bolster, Clifton O. Bingham, Tuhina Neogi, Yvonne C. Lee   +10 more
wiley   +1 more source

Scintigraphic assessment of osteoarthritis of the knee joint. [PDF]

, 1992
F McCrae, J Shouls, Paul Dieppe, I. Watt
openalex   +1 more source

Rehabilitation Interventions Delivered via Telehealth to Support Self‐Management of Rheumatic and Musculoskeletal Disease: A Scoping Review

Arthritis &Rheumatology, EarlyView.
Objective To identify and summarize existing telerehabilitation interventions for people living with rheumatic and musculoskeletal diseases (RMDs), including the rehabilitation components, the technology used, the type of health care professional (HCP) interaction, and how the effectiveness is evaluated.
Thomas A. Ingram, Rosemarie Barnett, Nuzhat Shakaib, Simon Jones, Raj Sengupta, Peter C. Rouse   +5 more
wiley   +1 more source

Trends and Regional Variation in Hip, Knee and Shoulder Replacement [PDF]

, 2010
Analyzes patterns in underuse or overuse of joint replacements among Medicare beneficiaries by geographic regions and race/ethnicity. Explores underlying factors and highlights the need for physician and patient education and shared decision ...
Amos R. Esty, David C. Goodman, Elliott S. Fisher, Ivan M. Tomek, John-Erik Bell   +4 more
core   +1 more source

Monocyte‐Derived Macrophages‐Synovial Fibroblasts Crosstalk Unravels Oncostatin Signaling Network as a Driver of Synovitis in Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis (OA) is a debilitating joint disease that is characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Damien Laouteouet, Olivier Bortolotti, Léa Marineche, Nicole Hannemann, Manon Chambon, Yaël Glasson, Anne‐Sophie Dumé, Julien De Lima, Maud Fournial, Dylan Touchet, Dany Séverac, Felicia Leccia, Christophe Duperray, Henri‐Alexandre Michaud, Farida Djouad, Benoît Le Goff, Frédéric Blanchard, Florence Apparailly, Gabriel Courties   +18 more
wiley   +1 more source

LOXL2 in anabolic response to chondrodysplasia mice progressive TMJ and knee osteoarthritis [PDF]

, 2019
Osteoarthritis (OA) is a degenerative joint disease that affects an estimated 9.6 % of men and 18 % of women over 60 years of age. However, there is no chondroprotective agent that is approved for clinical application.
Alsaqer, Saqer
core  

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source