Results 121 to 130 of about 137,909 (312)

Safety and Treatment Effectiveness of a Single Autologous Protein Solution Injection in Patients with Knee Osteoarthritis [PDF]

, 2016
Rogier A.M. van Drumpt, Walter van der Weegen, William J. King, Krista Toler, M. Mason Macenski   +4 more
openalex   +1 more source

Assessing Implant Stability in Cementless Femoral Components With Different Interference Fits

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Cementless total knee arthroplasty implants offer advantages over cemented implants, such as bone preservation and easier revision procedures. However, the optimal interference fit required to achieve a good press‐fit fixation, essential for both primary and long‐term stability, remains uncertain.
Esther Sánchez, Christoph Schilling, Thomas M. Grupp, Alexander Giurea, Nico Verdonschot, Dennis Janssen   +5 more
wiley   +1 more source

Dynamic Margin of Stability During Walking Differs Between End‐Stage Hip, Knee, and Ankle Arthritis

Journal of Orthopaedic Research, EarlyView.
ABSTRACT End‐stage arthritis of the hip, knee, or ankle leads to differential gait adaptations, but the differences in gait stability remain poorly understood. This study examined whether dynamic gait stability differed between patients with end‐stage hip arthritis (HA), knee arthritis (KA) and ankle arthritis (AA), and matched healthy controls (HC ...
Renoa Choudhury, Sara L. Arena, Robin M. Queen   +2 more
wiley   +1 more source

Association of rs763780 variation in interleukin 17F gene with the risk of knee osteoarthritis

Fiyz̤, 2019
Background: The injuries in osteoarthritis are mediated by various cytokines, growth factors, and inflammatory factors and the importance of the interleukin 17 family in this disease is increasingly evident.
Hassan Hassani-Bafrani, Monavareh Ahmadi , Gholam Reza Khosravi, Erfan Khosravi , Mohammad Karimian   +4 more
doaj  

Factors Affecting the Walking Speed of Patients with Knee Osteoarthritis

, 2015
Takumi Kobayashi, Masanori Yamanaka, T. Kannari, H. Horiuchi, N. Matsui, K. Kakuse, K. Nodin, M. Okawa, M. Tanaka, Masahiro SHIDA   +9 more
openalex   +2 more sources

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Circulating miR-126-3p is a mechanistic biomarker for knee osteoarthritis

Nature Communications
Osteoarthritis is a major contributor to pain and disability worldwide, yet there are currently no validated soluble biomarkers or disease-modifying treatments.
Thomas G. Wilson, Madhu Baghel, Navdeep Kaur, Indrani Datta, Ian Loveless, Pratibha Potla, Devin Mendez, Logan Hansen, Kevin Baker, T. Sean Lynch, Vasilios Moutzouros, Jason Davis, Shabana Amanda Ali   +12 more
doaj   +1 more source

630 About the FTA and the Stress distribution on the Knee Osteoarthritis Treatment

, 2006
Yoko Fujiyama, Tsutomu EZUMI
openalex   +2 more sources

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Treatment of large chondral lesions with an autologous minced cartilage technique and synovial flap leads to superior results compared to matrix associated autologous chondrocyte transplantation technique after 24 months: A controlled clinical trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr, Franziska Warth, Nicola Oehler, Martin Majewski, Christoph Lutter, Fabian Blanke   +5 more
wiley   +1 more source