Results 161 to 170 of about 146,940 (312)

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model

Advanced Science, EarlyView.
Longitudinal multifrequency magnetic resonance elastography (mMRE) performed on a clinical 3 Tesla magnetic resonance imaging system reveals early biomechanical alterations during liver tumor progression in a translational VX2 model. Changes in tumor stiffness and viscosity precede diffusion‐related alterations and are associated with extracellular ...
Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A. S. Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N. Müller, Ingolf Sack, Jing Guo, Shraga Nahum Goldberg, Lynn Jeanette Savic   +20 more
wiley   +1 more source

Joint line obliquity change was associated with femoral and tibial resection patterns and smaller final flexion imbalance after robot-assisted total knee arthroplasty. [PDF]

J Exp Orthop
Morita Y, Shin J, El-Hassan M, Shichman I, Long WJ, Sculco PK.   +5 more
europepmc   +1 more source

Protecting Your Knees and Back

, 2014
Many gardening tasks require knee and back strength and stability. The best way to protect knees and backs from the stress and strain is to condition them with strengthening exercises and ...
Predny, Mary Lorraine
core  

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

Posterior root repair with high tibial osteotomy improves radiological and clinical outcomes despite greater medial meniscus extrusion: A comparison of transtibial and all-inside techniques. [PDF]

J Exp Orthop
Fujie Y, Yasuda K, Yabuuchi K, Ebata T, Inoue M, Iwasaki N, Kondo E.   +6 more
europepmc   +1 more source

Cypress Knees, Gnarled and Fantastic in the Florida Cypress Gardens

, 1900
Cypress knees fill the shallower waters around Florida Cypress Gardens.https://digitalcommons.usf.edu/dunn_postcards/1687/thumbnail ...
Dunn, Hampton
core  

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Clinical Outcomes and Repeat-CRFA-Free Survival After Ultrasound-Guided Cooled Radiofrequency Ablation Using the Matsuoka Direct Nerve Targeting (MDNT) Technique for Knee Osteoarthritis: A Retrospective Cohort Study of 1,025 Consecutive Knees. [PDF]

J Pain Res
Matsuoka Y.
europepmc   +1 more source

Bud wearing camp shirt, with hands on knees in grass

, 1933
Bud wearing camp shirt, with hands on knees in grass.https://digitalcommons.usf.edu/wagner/1225/thumbnail ...
Nelson Poynter Memorial Library, Wagner, Francis G.   +1 more
core