Results 11 to 20 of about 344,176 (312)

Knock, knock, knocking on Europe’s door: Threat of leishmaniasis in Europe with a focus on Turkey

open access: yesCurrent Research in Parasitology and Vector-Borne Diseases, 2023
Leishmaniasis epidemiology is currently undergoing substantial transformations in both Turkey and Europe, signifying potential implications for public health.
Varol Tunalı, Ahmet Özbilgin
doaj   +2 more sources

Knock Knock

open access: yesKrisis, 2021
Henry Pickford
doaj   +3 more sources

Efficient biallelic knock-in in mouse embryonic stem cells by in vivo-linearization of donor and transient inhibition of DNA polymerase θ/DNA-PK

open access: yesScientific Reports, 2021
CRISPR/Cas9-mediated homology-directed repair (HDR) is used for error-free targeted knock-in of foreign donor DNA. However, the low efficiency of HDR-mediated knock-in hinders establishment of knock-in clones.
Daisuke Arai, Yoichi Nakao
doaj   +2 more sources

Octane Index Applicability over the Pressure-Temperature Domain

open access: yesEnergies, 2021
Modern boosted spark-ignition (SI) engines and emerging advanced compression ignition (ACI) engines operate under conditions that deviate substantially from the conditions of conventional autoignition metrics, namely the research and motor octane numbers
Tommy R. Powell   +6 more
doaj   +1 more source

Development and Experimental Validation of an Adaptive, Piston-Damage-Based Combustion Control System for SI Engines: Part 2—Implementation of Adaptive Strategies

open access: yesEnergies, 2021
This work focuses on the implementation of innovative adaptive strategies and a closed-loop chain in a piston-damage-based combustion controller. In the previous paper (Part 1), implemented models and the open loop algorithm are described and validated ...
Alessandro Brusa   +7 more
doaj   +1 more source

Massively parallel knock-in engineering of human T cells

open access: yesNature Biotechnology, 2023
The efficiency of targeted knock-in for cell therapeutic applications is generally low, and the scale is limited. In this study, we developed CLASH, a system that enables high-efficiency, high-throughput knock-in engineering.
Xiaoyun Dai   +14 more
semanticscholar   +1 more source

dCas9-based gene editing for cleavage-free genomic knock-in of long sequences

open access: yesNature Cell Biology, 2022
Gene editing is a powerful tool for genome and cell engineering. Exemplified by CRISPR–Cas, gene editing could cause DNA damage and trigger DNA repair processes that are often error-prone.
Chengkun Wang   +6 more
semanticscholar   +1 more source

Development and Experimental Validation of an Adaptive, Piston-Damage-Based Combustion Control System for SI Engines: Part 1—Evaluating Open-Loop Chain Performance

open access: yesEnergies, 2021
This work is focused on the development and validation of a spark advance controller, based on a piston “damage” model and a predictive knock model.
Alessandro Brusa   +7 more
doaj   +1 more source

Numerical Study of Knocking Combustion in a Heavy-Duty Engine under Plateau Conditions

open access: yesEnergies, 2022
Diesel engine combustion becomes very rough and can lead even lead to deflagration under high altitude conditions, which is harmful to component durability.
Haiying Li   +7 more
doaj   +1 more source

Knock, Knock: Who’s There? [PDF]

open access: yesCirculation, 2013
It has become apparent that major sources of reactive oxygen species (ROS) in mammalian cells are the NADPH oxidases. These multimeric enzymes are composed of membrane-bound catalytic subunits, or Nox enzymes, and a small docking subunit called p22phox.
Hana A, Itani   +2 more
openaire   +2 more sources

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