Results 31 to 40 of about 344,176 (312)
, 2021 Engine knock remains one of the major barriers to further improvement in thermal efficiency of Direct-Injection Spark-Ignition (DISI) engines. While Research Octane Number and Motor Octane Number are often used as standard rating methods for knock ...
Zongyu Yue, S. Som
semanticscholar +1 more source
Glia, 2021 Previous studies suggest that microglial‐expressed Apolipoprotein E (ApoE) is necessary to shift microglia into a neurodegenerative transcriptional state in Alzheimer's disease (AD) mouse models. On the other hand, elimination of microglia shifts amyloid
Caden M. Henningfield +4 more
semanticscholar +1 more source
Biological plasticity rescues target activity in CRISPR knock outs
Nature Methods, 2019 Gene knock outs (KOs) are efficiently engineered through CRISPR–Cas9-induced frameshift mutations. While the efficiency of DNA editing is readily verified by DNA sequencing, a systematic understanding of the efficiency of protein elimination has been ...
A. H. Smits +17 more
semanticscholar +1 more source
Molecular Metabolism, 2019 Objective Nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of advanced chronic liver disease. The progression of NAFLD, including nonalcoholic steatohepatitis (NASH), has a strong genetic component, and the most robust contributor is ...
D. Lindén +23 more
semanticscholar +1 more source
CHOOSING AND SUBSTANTIATION OF COMPRESSION RATIO OF THE GAS ENGINE CONVERTED ON THE BASIS OF THE 4ДТНА1 DIEL ENGINE [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2014 The method of compression ratio choosing in spark ignition gas ICE has been described. The results of calculation to choose the compression ratio in the gas engine 4ГЧН8,8/8,2 have been shown.
F. Abramchuk +3 more
doaj
Sexual Dimorphism in Balance and Coordination in p75NTRexonIII Knock-Out Mice
Frontiers in Behavioral Neuroscience, 2022 The p75 neurotrophin receptor (p75NTR) is implicated in various biological functions during development and adulthood. Several animal models have been developed to identify the roles of p75NTR in vivo and in vitro. P75NTRExonIII knock-out mice are widely
Mahdi Abbasian +2 more
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Cell, 2018 SUMMARY Huntington’s disease (HD) is characterized by the preferential loss of the medium spiny neurons in the striatum. Using CRISPR-Cas9 and somatic nuclear transfer technology, we established a knock-in (KI) pig model of HD that endogenously expresses
Sen Yan +20 more
semanticscholar +1 more source
Nihon Kikai Gakkai ronbunshu, 2017 This paper studies the condition of reducing knock intensity which is the pressure oscillation initiated by auto-ignition of the end gas. The knock intensity is thought to be decreased by suppressing the reaction rate of auto-ignition. In this study, the
Mitsuaki OHTOMO +3 more
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Efficient scar-free knock-ins of several kilobases in plants by engineered CRISPR/Cas endonucleases.
Molecular PlantIn plants and mammals, non-homologous end-joining is the dominant pathway to repair DNA double strand breaks, making it challenging to generate knock-in events.
T. Schreiber +9 more
semanticscholar +1 more source
Energy, 2021 Controlled knock combustion is the focus of academic and industrial research for modern spark-ignition engines to achieve higher thermal efficiency and better performance.
Hao Shi +4 more
semanticscholar +1 more source