Results 31 to 40 of about 277,472 (265)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Energies, 2019 Knock and super-knock are abnormal combustion phenomena in engines, however, they are hard to study comprehensively through optical experimental methods due to their inherent destructive nature.
Lijia Zhong, Changwen Liu
doaj +1 more source
Tapuya, 2020 Informal settlements present a challenge for fire safety because they lack the regulation of building standards that have been central to reducing fire risks elsewhere.
Graham Spinardi +2 more
doaj +1 more source
Study on joint detection of fabricated concrete shear wall based on percussion method [PDF]
MATEC Web of Conferences, 2019 The knock detection method is one of the non-destructive testing methods for assembly prefabricated components. The knocker is used to knock on the concrete prefabricated components to be tested.
Song Bo, Li Jian, Wang Man sheng
doaj +1 more source
Efficient DNA knock-in using AAV-mediated delivery with 2-cell embryo CRISPR-Cas9 electroporation
Frontiers in Genome Editing, 2023 Recent advances in CRISPR-Cas genome editing technology have been instrumental in improving the efficiency to produce genetically modified animal models.
Daniel J. Davis +6 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Effect of fuel-air mixture dilution on knock intensity
Nihon Kikai Gakkai ronbunshu, 2016 Effect of fuel-air mixture diluted by inert gas on knock intensity was investigated by using a rapid compression and expansion machine. Dilution of fuel-air mixture decreased knock intensity.
Mitsuaki OHTOMO +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Knock-Prediction System for Kerosene Engines Using In-Cylinder Pressure Signal
Energies, 2023 Piston engines fueled by kerosene have a strong application prospect in special vehicles and small aircrafts, but the low amount of octane in kerosene fuel causes its knock combustion phenomenon to be particularly serious.
Zhixin Xu +5 more
doaj +1 more source