Results 51 to 60 of about 344,176 (312)

Mixture Density Networks-Based Knock Simulator [PDF]

IEEE/ASME transactions on mechatronics, 2020
The engine knock simulator is useful for the evaluation of the feedback knock controllers and also the calibration of the feedforward control input without experiments in spark-ignition engines. This article proposes a mixture density network (MDN)-based
Xun Shen, Tinghui Ouyang, C. Khajorntraidet, Yuanchao Li, Shuai Li, J. Zhuang   +5 more
semanticscholar   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Easi-CRISPR protocol for creating knock-in and conditional knockout mouse models using long ssDNA donors

Nature Protocols, 2017
This protocol describes Easi-CRISPR, a method for creating knock-in, conditional knockout, and knockdown mouse models by CRISPR/Cas9-based genome engineering using long single-stranded DNA donor templates.
Hiromi Miura, R. Quadros, C. Gurumurthy, M. Ohtsuka   +3 more
semanticscholar   +1 more source

Numerical Analysis of End-Gas Autoignition and Pressure Oscillation in a Downsized SI Engine Using Large Eddy Simulation

Energies, 2019
Knock and super-knock are abnormal combustion phenomena in engines, however, they are hard to study comprehensively through optical experimental methods due to their inherent destructive nature.
Lijia Zhong, Changwen Liu
doaj   +1 more source

Proximal design in South African informal settlements: users as designers and the construction of the built environment and its fire risks

Tapuya, 2020
Informal settlements present a challenge for fire safety because they lack the regulation of building standards that have been central to reducing fire risks elsewhere.
Graham Spinardi, S.J. Cooper-Knock, David Rush   +2 more
doaj   +1 more source

Study on joint detection of fabricated concrete shear wall based on percussion method [PDF]

MATEC Web of Conferences, 2019
The knock detection method is one of the non-destructive testing methods for assembly prefabricated components. The knocker is used to knock on the concrete prefabricated components to be tested.
Song Bo, Li Jian, Wang Man sheng
doaj   +1 more source

Efficient DNA knock-in using AAV-mediated delivery with 2-cell embryo CRISPR-Cas9 electroporation

Frontiers in Genome Editing, 2023
Recent advances in CRISPR-Cas genome editing technology have been instrumental in improving the efficiency to produce genetically modified animal models.
Daniel J. Davis, James F. McNew, Hailey Maresca-Fichter, Kaiwen Chen, Bhanu P. Telugu, Elizabeth C. Bryda, Elizabeth C. Bryda   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice

EMBO Molecular Medicine, 2018
Normal hearing and synaptic transmission at afferent auditory inner hair cell (IHC) synapses require otoferlin. Deafness DFNB9, caused by mutations in the OTOF gene encoding otoferlin, might be treated by transferring wild‐type otoferlin cDNA into IHCs ...
H. Al-Moyed, A. Cepeda, Sangyong Jung, T. Moser, S. Kügler, E. Reisinger   +5 more
semanticscholar   +1 more source

Effect of fuel-air mixture dilution on knock intensity

Nihon Kikai Gakkai ronbunshu, 2016
Effect of fuel-air mixture diluted by inert gas on knock intensity was investigated by using a rapid compression and expansion machine. Dilution of fuel-air mixture decreased knock intensity.
Mitsuaki OHTOMO, Seiji YAMAMOTO, Hiroshi MIYAGAWA   +2 more
doaj   +1 more source