Results 61 to 70 of about 754,154 (303)
Neuronal human BACE1 knock-in induces systemic diabetes in mice [PDF]
, 2016 Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R.
Dekeryte, Ruta +12 more
core +4 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Experimental Investigation on Knock Characteristics from Pre-Chamber Gas Engine Fueled by Hydrogen
EnergiesHydrogen-fueled engines require large values of the excess air ratio in order to achieve high thermal efficiency. A low value of this coefficient promotes knocking combustion.
Ireneusz Pielecha +2 more
doaj +1 more source
CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. [PDF]
, 2014 Early on, corticotropin-releasing factor (CRF), a hallmark brain peptide mediating many components of the stress response, was shown to affect food intake inducing a robust anorexigenic response when injected into the rodent brain.
Stengel, Andreas, Taché, Yvette
core +3 more sources
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Porcine Knock-in Fibroblasts Expressing hDAF on α-1,3-Galactosyltransferase (GGTA1) Gene Locus [PDF]
Asian-Australasian Journal of Animal Sciences, 2012 The Galactose-α1,3-galactose (α1,3Gal) epitope is responsible for hyperacute rejection in pig-to-human xenotransplantation. Human decay-accelerating factor (hDAF) is a cell surface regulatory protein that serves as a complement inhibitor to protect self ...
Ji Woo Kim +3 more
doaj +1 more source
Neutrino interactions with nuclei [PDF]
, 2009 We present a model for neutrino-nucleus scattering in the energy region relevant for present and forthcoming neutrino-oscillation experiments. The model is based on the RPA treatment of the nuclear responses in the quasi-elastic and Delta-resonance ...
Federico Sanchez +6 more
core +3 more sources
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
How Can a Punch Knock You Out?
Frontiers in Neurology, 2020 Several hypotheses have been put forth over time to explain how consciousness can be so rapidly lost, and then spontaneously regained, following mechanical head trauma.
Anders Hånell +2 more
doaj +1 more source
Separation and identification of dominant mechanisms in double photoionization
, 2002 Double photoionization by a single photon is often discussed in terms of two contributing mechanisms, {\it knock-out} (two-step-one) and {\it shake-off} with the latter being a pure quantum effect.
A. Dalgarno +12 more
core +1 more source